{"title":"花生酱被确认为2024年英国婴儿肉毒杆菌中毒病例的来源。","authors":"Rosie J Crane, Corinne Fl Amar, Humphrey Omoruyi, Burhan Ahmed, Jonathan Finch, Rachael Kendrick, Shamez Ladhani, Anais Painset, Dunstan Rajendram, Nika Raphaely, Buvana Dwarakanathan, Suba Guruprasad, Hani Zuhur-Adi, Vanessa K Wong, Gauri Godbole","doi":"10.2807/1560-7917.ES.2025.30.30.2500512","DOIUrl":null,"url":null,"abstract":"<p><p>A 6-month-old infant was hospitalised with suspected infant botulism after being given peanut butter to reduce their risk of developing peanut allergy. <i>Clostridium botulinum</i> type A was detected in their faeces and the peanut butter by PCR and culture. Whole genome sequencing confirmed identical strains, identifying the peanut butter as the source of infection. The infant was treated with human-derived antitoxin Botulism Immune Globulin Intravenous (Human) (BIG-IV) and recovered well. This case highlights potential botulism risk with early peanut introduction.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 30","pages":""},"PeriodicalIF":7.8000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315516/pdf/","citationCount":"0","resultStr":"{\"title\":\"Peanut butter confirmed as the source in a case of infant botulism, United Kingdom, 2024.\",\"authors\":\"Rosie J Crane, Corinne Fl Amar, Humphrey Omoruyi, Burhan Ahmed, Jonathan Finch, Rachael Kendrick, Shamez Ladhani, Anais Painset, Dunstan Rajendram, Nika Raphaely, Buvana Dwarakanathan, Suba Guruprasad, Hani Zuhur-Adi, Vanessa K Wong, Gauri Godbole\",\"doi\":\"10.2807/1560-7917.ES.2025.30.30.2500512\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 6-month-old infant was hospitalised with suspected infant botulism after being given peanut butter to reduce their risk of developing peanut allergy. <i>Clostridium botulinum</i> type A was detected in their faeces and the peanut butter by PCR and culture. Whole genome sequencing confirmed identical strains, identifying the peanut butter as the source of infection. The infant was treated with human-derived antitoxin Botulism Immune Globulin Intravenous (Human) (BIG-IV) and recovered well. This case highlights potential botulism risk with early peanut introduction.</p>\",\"PeriodicalId\":12161,\"journal\":{\"name\":\"Eurosurveillance\",\"volume\":\"30 30\",\"pages\":\"\"},\"PeriodicalIF\":7.8000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315516/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eurosurveillance\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2807/1560-7917.ES.2025.30.30.2500512\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eurosurveillance","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2807/1560-7917.ES.2025.30.30.2500512","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Peanut butter confirmed as the source in a case of infant botulism, United Kingdom, 2024.
A 6-month-old infant was hospitalised with suspected infant botulism after being given peanut butter to reduce their risk of developing peanut allergy. Clostridium botulinum type A was detected in their faeces and the peanut butter by PCR and culture. Whole genome sequencing confirmed identical strains, identifying the peanut butter as the source of infection. The infant was treated with human-derived antitoxin Botulism Immune Globulin Intravenous (Human) (BIG-IV) and recovered well. This case highlights potential botulism risk with early peanut introduction.
期刊介绍:
Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.