{"title":"艾滋病毒生物医学预防的社区方面。","authors":"Bruno Spire, Marion di Ciaccio","doi":"10.1146/annurev-pharmtox-062124-044855","DOIUrl":null,"url":null,"abstract":"<p><p>Although HIV treatment and prevention efforts in recent decades have significantly reduced new infections and mortality worldwide, progress has been uneven. Regions with the highest prevalence are those where HIV control programs fail to reach key populations, such as people who inject drugs, men who have sex with men, transgender people, and certain ethnic minorities. More specifically, the rollout of proven HIV prevention tools in these populations, such as antiretroviral therapy and pre-exposure prophylaxis, still presents a challenge. Community-based organizations play a key role in facilitating access to testing and treatment, particularly through rapid testing programs and peer support. These initiatives are crucial for overcoming social and cultural barriers, reducing stigma, and ensuring treatment adherence, especially among key populations.</p>","PeriodicalId":8057,"journal":{"name":"Annual review of pharmacology and toxicology","volume":" ","pages":""},"PeriodicalIF":13.1000,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Community Aspects of HIV Biomedical Prevention.\",\"authors\":\"Bruno Spire, Marion di Ciaccio\",\"doi\":\"10.1146/annurev-pharmtox-062124-044855\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Although HIV treatment and prevention efforts in recent decades have significantly reduced new infections and mortality worldwide, progress has been uneven. Regions with the highest prevalence are those where HIV control programs fail to reach key populations, such as people who inject drugs, men who have sex with men, transgender people, and certain ethnic minorities. More specifically, the rollout of proven HIV prevention tools in these populations, such as antiretroviral therapy and pre-exposure prophylaxis, still presents a challenge. Community-based organizations play a key role in facilitating access to testing and treatment, particularly through rapid testing programs and peer support. These initiatives are crucial for overcoming social and cultural barriers, reducing stigma, and ensuring treatment adherence, especially among key populations.</p>\",\"PeriodicalId\":8057,\"journal\":{\"name\":\"Annual review of pharmacology and toxicology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":13.1000,\"publicationDate\":\"2025-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annual review of pharmacology and toxicology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1146/annurev-pharmtox-062124-044855\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual review of pharmacology and toxicology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1146/annurev-pharmtox-062124-044855","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Although HIV treatment and prevention efforts in recent decades have significantly reduced new infections and mortality worldwide, progress has been uneven. Regions with the highest prevalence are those where HIV control programs fail to reach key populations, such as people who inject drugs, men who have sex with men, transgender people, and certain ethnic minorities. More specifically, the rollout of proven HIV prevention tools in these populations, such as antiretroviral therapy and pre-exposure prophylaxis, still presents a challenge. Community-based organizations play a key role in facilitating access to testing and treatment, particularly through rapid testing programs and peer support. These initiatives are crucial for overcoming social and cultural barriers, reducing stigma, and ensuring treatment adherence, especially among key populations.
期刊介绍:
Since 1961, the Annual Review of Pharmacology and Toxicology has been a comprehensive resource covering significant developments in pharmacology and toxicology. The journal encompasses various aspects, including receptors, transporters, enzymes, chemical agents, drug development science, and systems like the immune, nervous, gastrointestinal, cardiovascular, endocrine, and pulmonary systems. Special topics are also featured in this annual review.