Compound lidocaine cream with warm compress for pain relief in ultrasound-guided peripherally inserted central catheter placement for cancer patients.
Background: Ultrasound-guided peripherally inserted central catheter (PICC) placement is vital for cancer therapy, but lidocaine infiltration faces limitations like puncture pain and vasospasm.
Aim: To assess the clinical efficacy of a no-pain intervention-combining compound lidocaine cream with warm compress-in reducing pain during ultrasound-guided PICC placement in cancer patients.
Methods: A retrospective cohort study analyzed 88 cancer patients undergoing PICC placement (Shanghai Fourth People's Hospital, 2024). Patients were divided into control (lidocaine infiltration, n = 44) and intervention (cream + warm compress, n = 44) groups. Primary outcomes: Pain scores (numerical rating scale), procedural time, complications; secondary outcome: Satisfaction.
Results: The intervention group showed significantly lower pain scores (1.2 ± 0.4 vs 3.8 ± 1.2, P = 0.012) with comparable first-attempt success (95.5% vs 90.9%) and safety (P = 0.672). Thermal activation of transient receptor potential vanilloid 1 channel enhanced drug penetration, achieving anesthesia within 8-10 minutes. Patient satisfaction reached 97.7%.
Conclusion: The combination of compound lidocaine cream with warm compress significantly alleviates procedural pain and enhances patient satisfaction during ultrasound-guided PICC placement in cancer patients, supporting its clinical application.
期刊介绍:
The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.