影响子宫内膜异位症患者腹腔镜手术后体外受精成功的因素。

Q2 Medicine
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-04-29 eCollection Date: 2025-01-01 DOI:10.47176/mjiri.39.61
Abolfazl Mehdizadehkashi, Shahla Chaichian, Roya Derakhshan, Farahnaz Farzaneh, Azam Govahi, Azar Mohammadzadeh, Banafsheh Nikfar, Yasaman Kabir Anaraki
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引用次数: 0

摘要

背景:考虑到腹腔镜手术对子宫内膜异位症患者体外受精成功率影响的证据质量不高,我们的研究旨在评估子宫内膜异位症相关性不孕症患者行腹腔镜手术的体外受精成功率及其影响因素。方法:在一项回顾性队列研究中,我们纳入了在一所大学医院接受腹腔镜手术的15至40岁诊断为子宫内膜异位症相关不孕症的妇女。患有严重男性因素性不孕症、bbb、子宫肌瘤、卵巢早衰、信息不完整或无法获得不育中心数据的女性被排除在外。数据从伊朗医科大学批准的子宫内膜异位症数据登记处收集,代码为1400-2-65-21233,包括年龄、体重指数、不孕症持续时间、子宫内膜异位症严重程度和体外受精前的抗雷氏激素水平。体外受精的成功是通过超声检查中的胚胎心跳识别来考虑的,即临床妊娠。单变量分析采用独立样本t检验、Mann-Whitney检验和卡方检验,多变量分析采用logistic回归。结果:55例符合条件的患者中,试管婴儿成功率23例(41.81%)。参与者平均年龄34.98岁,标准差5.93岁。42名(76%)参与者观察到子宫内膜异位瘤;单侧子宫内膜瘤比双侧更常见(25例[45.5%]vs 17例[30.9%])。在临床和人口学特征方面,体外受精阳性组和体外受精阴性组之间没有明显差异。结论:腹腔镜手术治疗深浸润性子宫内膜异位症可提高体外受精成功率和妊娠率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Factors Affecting IVF Success after Laparoscopic Surgery in Women with Endometriosis.

Factors Affecting IVF Success after Laparoscopic Surgery in Women with Endometriosis.

Background: Considering low-quality evidence regarding the impact of laparoscopic surgery on in vitro fertilization (IVF) success rates in women with endometriosis, our research aimed to evaluate IVF success rates and their influential factors in women with endometriosis-related infertility who underwent laparoscopic surgery.

Methods: In a retrospective cohort study, we included women aged 15 to 40 years diagnosed with endometriosis-related infertility who underwent laparoscopic surgery in a university hospital. Women with severe male factor infertility, adenomyosis, uterine myomas, premature ovarian insufficiency, incomplete information, or inaccessible data from infertility centers were excluded. Data were collected from the Endometriosis Data Registry approved by the Iran University of Medical Sciences under code number 1400-2-65-21233, including age, body mass index, infertility duration, endometriosis severity, and Anti-Müllerian hormone levels before IVF. IVF success was considered by an embryonic heartbeat identification during an ultrasound exam, that is, a clinical pregnancy. Independent sample t test, Mann-Whitney, and chi-square tests were applied for single-variable analysis, and logistic regression was used for multivariable analysis.

Results: Of 55 eligible patients, IVF was successful in 23 (41.81%). The mean age of participants was 34.98 years, with a standard deviation of 5.93 years. Endometriomas were observed in 42 (76%) of the participants; unilateral endometriomas were more common than bilateral (25 [45.5%] vs 17 [30.9%]). No significant differences were identified between the IVF-positive and IVF-negative groups regarding clinical and demographic characteristics.

Conclusion: Laparoscopic surgery in women with deep infiltrating endometriosis enhances IVF success and increases pregnancy rate.

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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
90
审稿时长
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