{"title":"高效液相色谱法同时测定个人护理用品中氨基酸表面活性剂n -月桂酰肌氨酸钠和甲基椰油酰牛磺酸钠的含量。","authors":"Kumar Thangarathinam, Udhayachandran Narayanan","doi":"10.1093/chromsci/bmaf044","DOIUrl":null,"url":null,"abstract":"<p><p>Sodium N-lauroylsarcosinate (NLS) and sodium methyl cocoyl taurate (SMCT) are widely used in sulfate free personal care products. We present a straightforward and highly sensitive High-Performance Liquid Chromatographic (HPLC) method for simultaneous detection and estimation of these substances in commercial personal care products. The HPLC method has a detection limit for NLS of concentrations as low as 1.5 ppm, and that for SMCT of 4.0 ppm, all with a signal-to-noise (S/N) ratio exceeding 3.0. Additionally, the method enables quantification down to 4.5 ppm for NLS, and 12.0 ppm for SMCT, with an S/N ratio surpassing 10.0. This validated method serves as a versatile tool for the accurate quantification of NLS, and SMCT in sulfate free personal care products like shampoos, face washes, body washes, baby shampoos, and toothpastes.</p>","PeriodicalId":15430,"journal":{"name":"Journal of chromatographic science","volume":"63 7","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Method for Simultaneous Determination of Amino Acid Surfactants Sodium N-Lauroylsarcosinate and Sodium Methyl Cocoyl Taurate in Personal Care Products, by Using High Performance Liquid Chromatography.\",\"authors\":\"Kumar Thangarathinam, Udhayachandran Narayanan\",\"doi\":\"10.1093/chromsci/bmaf044\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Sodium N-lauroylsarcosinate (NLS) and sodium methyl cocoyl taurate (SMCT) are widely used in sulfate free personal care products. We present a straightforward and highly sensitive High-Performance Liquid Chromatographic (HPLC) method for simultaneous detection and estimation of these substances in commercial personal care products. The HPLC method has a detection limit for NLS of concentrations as low as 1.5 ppm, and that for SMCT of 4.0 ppm, all with a signal-to-noise (S/N) ratio exceeding 3.0. Additionally, the method enables quantification down to 4.5 ppm for NLS, and 12.0 ppm for SMCT, with an S/N ratio surpassing 10.0. This validated method serves as a versatile tool for the accurate quantification of NLS, and SMCT in sulfate free personal care products like shampoos, face washes, body washes, baby shampoos, and toothpastes.</p>\",\"PeriodicalId\":15430,\"journal\":{\"name\":\"Journal of chromatographic science\",\"volume\":\"63 7\",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of chromatographic science\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1093/chromsci/bmaf044\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chromatographic science","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1093/chromsci/bmaf044","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
摘要
n -月桂酰肌氨酸钠(NLS)和甲基椰油酰牛磺酸钠(SMCT)广泛用于无硫酸盐个人护理产品中。我们提出了一种简单、高灵敏度的高效液相色谱(HPLC)方法,用于同时检测和估计商业个人护理产品中这些物质。该方法的检出限低至1.5 ppm的NLS,低至4.0 ppm的SMCT,信噪比均大于3.0。此外,该方法可使NLS的定量低至4.5 ppm, SMCT的定量低至12.0 ppm,信噪比超过10.0。此验证方法可作为准确定量无硫酸盐个人护理产品(如洗发水,洗面奶,沐浴露,婴儿洗发水和牙膏)中NLS和SMCT的通用工具。
Method for Simultaneous Determination of Amino Acid Surfactants Sodium N-Lauroylsarcosinate and Sodium Methyl Cocoyl Taurate in Personal Care Products, by Using High Performance Liquid Chromatography.
Sodium N-lauroylsarcosinate (NLS) and sodium methyl cocoyl taurate (SMCT) are widely used in sulfate free personal care products. We present a straightforward and highly sensitive High-Performance Liquid Chromatographic (HPLC) method for simultaneous detection and estimation of these substances in commercial personal care products. The HPLC method has a detection limit for NLS of concentrations as low as 1.5 ppm, and that for SMCT of 4.0 ppm, all with a signal-to-noise (S/N) ratio exceeding 3.0. Additionally, the method enables quantification down to 4.5 ppm for NLS, and 12.0 ppm for SMCT, with an S/N ratio surpassing 10.0. This validated method serves as a versatile tool for the accurate quantification of NLS, and SMCT in sulfate free personal care products like shampoos, face washes, body washes, baby shampoos, and toothpastes.
期刊介绍:
The Journal of Chromatographic Science is devoted to the dissemination of information concerning all methods of chromatographic analysis. The standard manuscript is a description of recent original research that covers any or all phases of a specific separation problem, principle, or method. Manuscripts which have a high degree of novelty and fundamental significance to the field of separation science are particularly encouraged. It is expected the authors will clearly state in the Introduction how their method compares in some markedly new and improved way to previous published related methods. Analytical performance characteristics of new methods including sensitivity, tested limits of detection or quantification, accuracy, precision, and specificity should be provided. Manuscripts which describe a straightforward extension of a known analytical method or an application to a previously analyzed and/or uncomplicated sample matrix will not normally be reviewed favorably. Manuscripts in which mass spectrometry is the dominant analytical method and chromatography is of marked secondary importance may be declined.