儿童主动脉瓣疾病的最佳手术策略是什么?

IF 0.7 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiology in the Young Pub Date : 2025-09-01 Epub Date: 2025-07-31 DOI:10.1017/S1047951125101121
Zhangwei Wang, Honghao Fu, Shoujun Li
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引用次数: 0

摘要

儿童主动脉瓣病变是心脏外科研究的热点。儿童主动脉瓣疾病的手术治疗受年龄、疾病严重程度和技术的影响。手术修复的主要目的是改善患儿的症状,尽可能避免或延迟人工瓣膜置换术和再手术。同时,手术修复要考虑手术效果的可持续性和术后主动脉瓣的生长能力。目前,仍缺乏一致的手术治疗理念和通用的手术治疗策略。根据目前发表的文献,我们得出结论,对于1岁以下的儿童,瓣膜修复是避免过早瓣膜置换术的首选。然而,对于经验丰富的医疗中心和外科医生来说,罗斯手术可以尝试治疗1岁以下儿童的主动脉瓣疾病,其长期效果与主动脉修复相当。在1岁以上的儿童中,修复和罗斯手术的总体结果相似。当术中获得可接受的结果时,修复的结果是有利的。然而,当术中修复效果不理想时,Ross手术效果较好。对于主动脉瓣修复不佳、Ross手术有禁忌症、不愿服用抗凝剂的患者,Ozaki手术也可能是延迟机械瓣膜置换术的一种选择。与主动脉瓣修复和Ross手术相比,机械或同种移植物主动脉瓣置换术预后较差,被认为是儿童主动脉瓣疾病手术治疗的最后选择。本文综述了几种不同手术方式治疗儿童主动脉瓣疾病的现状、优缺点及适用人群。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What is the best surgical strategy for aortic valve disease in children.

Aortic valve disease in children is a hot topic in the field of cardiac surgery. The surgical treatment of aortic valve disease in children is affected by age, severity of the disease, and technology. The main purpose of surgical repair is to improve the symptoms of children and avoid or delay prosthetic valve replacement and reoperation as much as possible. At the same time, surgical repair should take into account the sustainability of the surgical effect and the growth ability of the aortic valve after surgery. At present, there is still a lack of a consistent surgical treatment concept and a universal surgical treatment strategy. Based on the current published literature, we conclude that for children younger than 1 year, valve repair is the first choice to avoid premature valve replacement. However, for experienced medical centres and surgeons, the Ross procedure can be attempted to treat aortic valve disease in children younger than 1 year and the long-term effect is comparable to aortic repair. In children older than 1 year, overall outcomes were similar with repair and the Ross procedure. When an acceptable intraoperative result was achieved, the outcomes of repair were favourable. However, when the intraoperative result of repair was suboptimal, the Ross procedure showed better results. For patients with suboptimal aortic valve repair, contraindications to the Ross procedure, and unwillingness to take anticoagulants, Ozaki procedure may also be an option to delay mechanical valve replacement. Compared with aortic valve repair and the Ross procedure, mechanical or homograft aortic valve replacement has a poor prognosis and is considered as a last resort option for surgical treatment of aortic valve disease in children. This article reviews the current status, advantages and disadvantages, and suitable population of several different surgical procedures for aortic valve disease in children.

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来源期刊
Cardiology in the Young
Cardiology in the Young 医学-小儿科
CiteScore
1.70
自引率
10.00%
发文量
715
审稿时长
4-8 weeks
期刊介绍: Cardiology in the Young is devoted to cardiovascular issues affecting the young, and the older patient suffering the sequels of congenital heart disease, or other cardiac diseases acquired in childhood. The journal serves the interests of all professionals concerned with these topics. By design, the journal is international and multidisciplinary in its approach, and members of the editorial board take an active role in the its mission, helping to make it the essential journal in paediatric cardiology. All aspects of paediatric cardiology are covered within the journal. The content includes original articles, brief reports, editorials, reviews, and papers devoted to continuing professional development.
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