男性重症COVID-19的遗传易感性：雄激素受体CAG重复长度的影响

IF 0.9 Q4 GENETICS & HEREDITY

Gene Reports Pub Date : 2025-07-18 DOI:10.1016/j.genrep.2025.102299

Arsalan Eskandarinezhad , Asra Moradkhani , Mobin Azami , Efat Shafiei , Sabah Hasani , Abbas Aghaei , Nariman Moradi , Shahnaz Ghafouri , Naseh Sigari , Asaad Azarnezhad

引用次数: 0

摘要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Genetic susceptibility to severe COVID-19 in men: The impact of androgen receptor CAG repeat length

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Genetic susceptibility to severe COVID-19 in men: The impact of androgen receptor CAG repeat length

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来源期刊

Gene Reports Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

3.30

自引率

7.70%

发文量

246

审稿时长

49 days

期刊介绍： Gene Reports publishes papers that focus on the regulation, expression, function and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses. Gene Reports strives to be a very diverse journal and topics in all fields will be considered for publication. Although not limited to the following, some general topics include: DNA Organization, Replication & Evolution -Focus on genomic DNA (chromosomal organization, comparative genomics, DNA replication, DNA repair, mobile DNA, mitochondrial DNA, chloroplast DNA). Expression & Function - Focus on functional RNAs (microRNAs, tRNAs, rRNAs, mRNA splicing, alternative polyadenylation) Regulation - Focus on processes that mediate gene-read out (epigenetics, chromatin, histone code, transcription, translation, protein degradation). Cell Signaling - Focus on mechanisms that control information flow into the nucleus to control gene expression (kinase and phosphatase pathways controlled by extra-cellular ligands, Wnt, Notch, TGFbeta/BMPs, FGFs, IGFs etc.) Profiling of gene expression and genetic variation - Focus on high throughput approaches (e.g., DeepSeq, ChIP-Seq, Affymetrix microarrays, proteomics) that define gene regulatory circuitry, molecular pathways and protein/protein networks. Genetics - Focus on development in model organisms (e.g., mouse, frog, fruit fly, worm), human genetic variation, population genetics, as well as agricultural and veterinary genetics. Molecular Pathology & Regenerative Medicine - Focus on the deregulation of molecular processes in human diseases and mechanisms supporting regeneration of tissues through pluripotent or multipotent stem cells.