在急诊科筛查丙型肝炎

IF 51 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Nature Reviews Gastroenterology &Hepatology Pub Date : 2025-07-30 DOI:10.1038/s41575-025-01110-7

Eleni Kotsiliti

引用次数: 0

摘要

一项前瞻性、多中心、实用的随机临床试验（NCT04003454）评估了在急诊科筛查丙型肝炎病毒（HCV）感染患者的有效性。研究人员假设，与基于风险评估提供检测的靶向筛查相比，不考虑风险进行丙型肝炎检测的非靶向筛查能识别出更多的丙型肝炎患者。该试验在美国城市地区的三个急诊科进行，包括147,498例患者就诊，参与者年龄为29-57岁，其中51.1%为男性。患者被随机分配接受非靶向（n = 73,847）或靶向（n = 73,651） HCV感染筛查。主要结局是新诊断的HCV感染，次要结局包括丙型肝炎管理和全因死亡率（随访18个月）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Gastroenterology &Hepatology 医学-胃肠肝病学

CiteScore

52.30

自引率

0.60%

发文量

147

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.