自身免疫性风湿病和人群筛查的表现:一项共识发展研究

IF 1.9
Ling Xiang, Andrea Hsiu Ling Low, Ying Ying Leung, Warren Weng Seng Fong, Tang Ching Lau, Dow Rhoon Koh, Sungwon Yoon, Julian Thumboo
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引用次数: 0

摘要

自我管理的筛查问卷是缩短自身免疫性风湿病(ARDs)患者诊断延迟的关键策略之一。然而,大多数现有的ARDs筛查问卷都是为了筛查一种或有限数量的ARDs,因此当目标是筛查常见ARDs时,其效用有限。我们旨在制定ARDs人群筛查清单,并在此基础上编制ARDs筛查问卷。方法:本研究包括两个阶段:第一阶段涉及通过经修改的德尔福研究与经认证的风湿病学家一起制定ARDs清单,第二阶段涉及通过经修改的名义小组技术与经认证的风湿病学家、其他照顾ARDs患者的医疗保健专业人员以及ARDs患者一起制定ARDs表现清单。结果:在第一阶段,使用多管齐下的方法确定了14个候选ARDs,其中10个被认为需要在普通人群中进行筛选,通过三轮德尔菲练习。在第2阶段,从文献综述中确定了这10种ARDs的80种候选表现。其中,59种表现被认为有必要通过一轮命名前小组对话和两轮命名小组讨论在筛选问卷中进行评估。结论:本研究建立了基于共识的ARDs及其表现清单。为开发新的ARDs筛查问卷提供了基础,以促进一般人群ARDs的早期诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Autoimmune rheumatic diseases and manifestations for population screening: a consensus development study.

Introduction: Self-administered screening questionnaires are one of the key strategies to shorten diagnostic delay among patients with autoimmune rheumatic diseases (ARDs). However, most existing screening questionnaires for ARDs were developed to screen for one or a limited number of ARDs, and thus have limited utility when the goal is to screen for common ARDs. We aimed to develop a list of ARDs for population screening, and based on this, a list of manifestations to be assessed in a screening questionnaire for ARDs.

Methods: This study comprised two phases: Phase 1 involved the development of a list of ARDs through a modified Delphi study with accredited rheumatologists and Phase 2 involved the development of a list of manifestations through a modified nominal group technique with accredited rheumatologists, other healthcare professionals caring for patients with ARDs, and patients with ARDs.

Results: In Phase 1, 14 candidate ARDs were identified using a multipronged approach, ten of which were deemed necessary to be screened for in the general population, through three rounds of Delphi exercise. In Phase 2, 80 candidate manifestations of these ten ARDs were identified from a literature review. Of these, 59 manifestations were deemed necessary to be assessed in a screening questionnaire through one round of prenominal group dialogue and two rounds of nominal group discussion.

Conclusion: Consensus-based lists of ARDs and their manifestations were developed in this study. They provide a basis for developing new ARD screening questionnaires to facilitate early diagnosis of ARDs in the general population.

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