Vincenzo Barone, Daniele Petrini, Pier Luigi Surico, Sebastiano Nunziata, Claudia Scarani, Francesco Offi, Valentina Villani, Marco Coassin, Antonio Di Zazzo
{"title":"轮廓测量引导巩膜晶体改善视力和减少不规则角膜的眼像差：回顾性病例系列。","authors":"Vincenzo Barone, Daniele Petrini, Pier Luigi Surico, Sebastiano Nunziata, Claudia Scarani, Francesco Offi, Valentina Villani, Marco Coassin, Antonio Di Zazzo","doi":"10.1097/ICL.0000000000001199","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Scleral lenses (SLs) represent a key treatment for visual rehabilitation in patients with irregular corneas, such as keratoconus (KC), pellucid marginal degeneration (PMD), and postlaser in situ keratomileusis (LASIK) ectasia. This study evaluates the impact of profilometry-guided SLs on visual acuity (VA) and ocular aberrations in these patients.</p><p><strong>Methods: </strong>Medical records of 23 eyes from 23 patients with KC, PMD, and post-LASIK ectasia were reviewed. All patients were fitted with profilometry-guided SLs. High-contrast visual acuity (HCVA), low-contrast visual acuity (LCVA), and aberrometry parameters (Strehl ratio, higher-order root mean square (HO-RMS), coma, spherical aberration, and trefoil) were analyzed before and during SL wear.</p><p><strong>Results: </strong>HCVA improved significantly from 0.62±0.09 logMAR at baseline to 0.03±0.01 logMAR with SL wear ( P <0.05). LCVA also showed significant improvements ( P <0.05). HO-RMS decreased from 2.70±0.54 D to 1.00±0.20 D ( P <0.05), with notable reductions in coma (1.31±0.21 D to 0.49±0.04 D) and trefoil (1.26±0.29 D to 0.34±0.09 D).</p><p><strong>Conclusions: </strong>Profilometry-guided SLs significantly improve VA and reduce higher-order aberrations in patients with irregular corneas, offering an effective nonsurgical solution for enhancing vision quality in these complex cases.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"445-449"},"PeriodicalIF":2.1000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Profilometry-Guided Scleral Lenses Improve Visual Acuity and Reduce Ocular Aberrations in Irregular Corneas: A Retrospective Case Series.\",\"authors\":\"Vincenzo Barone, Daniele Petrini, Pier Luigi Surico, Sebastiano Nunziata, Claudia Scarani, Francesco Offi, Valentina Villani, Marco Coassin, Antonio Di Zazzo\",\"doi\":\"10.1097/ICL.0000000000001199\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Scleral lenses (SLs) represent a key treatment for visual rehabilitation in patients with irregular corneas, such as keratoconus (KC), pellucid marginal degeneration (PMD), and postlaser in situ keratomileusis (LASIK) ectasia. This study evaluates the impact of profilometry-guided SLs on visual acuity (VA) and ocular aberrations in these patients.</p><p><strong>Methods: </strong>Medical records of 23 eyes from 23 patients with KC, PMD, and post-LASIK ectasia were reviewed. All patients were fitted with profilometry-guided SLs. High-contrast visual acuity (HCVA), low-contrast visual acuity (LCVA), and aberrometry parameters (Strehl ratio, higher-order root mean square (HO-RMS), coma, spherical aberration, and trefoil) were analyzed before and during SL wear.</p><p><strong>Results: </strong>HCVA improved significantly from 0.62±0.09 logMAR at baseline to 0.03±0.01 logMAR with SL wear ( P <0.05). LCVA also showed significant improvements ( P <0.05). HO-RMS decreased from 2.70±0.54 D to 1.00±0.20 D ( P <0.05), with notable reductions in coma (1.31±0.21 D to 0.49±0.04 D) and trefoil (1.26±0.29 D to 0.34±0.09 D).</p><p><strong>Conclusions: </strong>Profilometry-guided SLs significantly improve VA and reduce higher-order aberrations in patients with irregular corneas, offering an effective nonsurgical solution for enhancing vision quality in these complex cases.</p>\",\"PeriodicalId\":50457,\"journal\":{\"name\":\"Eye & Contact Lens-Science and Clinical Practice\",\"volume\":\" \",\"pages\":\"445-449\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eye & Contact Lens-Science and Clinical Practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/ICL.0000000000001199\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/11 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eye & Contact Lens-Science and Clinical Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/ICL.0000000000001199","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Profilometry-Guided Scleral Lenses Improve Visual Acuity and Reduce Ocular Aberrations in Irregular Corneas: A Retrospective Case Series.
Objectives: Scleral lenses (SLs) represent a key treatment for visual rehabilitation in patients with irregular corneas, such as keratoconus (KC), pellucid marginal degeneration (PMD), and postlaser in situ keratomileusis (LASIK) ectasia. This study evaluates the impact of profilometry-guided SLs on visual acuity (VA) and ocular aberrations in these patients.
Methods: Medical records of 23 eyes from 23 patients with KC, PMD, and post-LASIK ectasia were reviewed. All patients were fitted with profilometry-guided SLs. High-contrast visual acuity (HCVA), low-contrast visual acuity (LCVA), and aberrometry parameters (Strehl ratio, higher-order root mean square (HO-RMS), coma, spherical aberration, and trefoil) were analyzed before and during SL wear.
Results: HCVA improved significantly from 0.62±0.09 logMAR at baseline to 0.03±0.01 logMAR with SL wear ( P <0.05). LCVA also showed significant improvements ( P <0.05). HO-RMS decreased from 2.70±0.54 D to 1.00±0.20 D ( P <0.05), with notable reductions in coma (1.31±0.21 D to 0.49±0.04 D) and trefoil (1.26±0.29 D to 0.34±0.09 D).
Conclusions: Profilometry-guided SLs significantly improve VA and reduce higher-order aberrations in patients with irregular corneas, offering an effective nonsurgical solution for enhancing vision quality in these complex cases.
期刊介绍：
Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.
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