代谢健康和不健康肥胖个体的脂质特征和动脉粥样硬化风险:性别和社会人口因素的队列分析

IF 1.9 Q3 PERIPHERAL VASCULAR DISEASE
Miguel García Samuelsson, Pedro Juan Tárraga López, Ángel Arturo López González, Carla Busquets-Cortés, Joan Obrador de Hevia, José Ignacio Ramírez Manent
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引用次数: 0

摘要

目的:分析代谢健康(MHO)或代谢不健康(MNHO)肥胖工人的脂质特征和与动脉粥样硬化风险相关的社会人口学因素。方法:对68884名肥胖工人进行横断面调查。评估致动脉粥样硬化脂质指数(总胆固醇/HDL-c、LDL-c/HDL-c、甘油三酯/HDL-c)和致动脉粥样硬化性血脂异常的患病率。多项逻辑回归确定了与血脂风险相关的因素。结果:MNHO个体在性别和诊断标准上表现出明显更高的动脉粥样硬化指数。动脉粥样硬化性血脂异常和脂质三联症在MNHO中更为普遍。男性、年龄较大、受教育程度较低、社会地位较低、缺乏体育锻炼、不坚持地中海饮食和吸烟与血脂风险升高有关。结论:尽管MHO个体表现出比MNHO更有利的脂质谱,但这种优势随着定义的不严格而减弱。社会人口和生活方式因素强烈调节动脉粥样硬化风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lipid profile and atherogenic risk in metabolically healthy and unhealthy obese individuals: A cohort analysis by sex and sociodemographic factors.

Objective: To analyze lipid profiles and sociodemographic factors associated with atherogenic risk in obese workers classified as metabolically healthy (MHO) or unhealthy (MNHO).

Methods: Cross-sectional study of 68,884 obese workers. Atherogenic lipid indices (total cholesterol/HDL-c, LDL-c/HDL-c, triglycerides/HDL-c) and prevalence of atherogenic dyslipidemia were assessed. Multinomial logistic regression identified factors linked to lipid risk.

Results: MNHO individuals exhibited significantly higher atherogenic indices across sexes and diagnostic criteria. Atherogenic dyslipidemia and lipid triad were more prevalent in MNHO. Male sex, older age, lower educational level, lower social class, physical inactivity, low adherence to the Mediterranean diet, and smoking were associated with higher lipid risk.

Conclusion: Although MHO individuals show a more favorable lipid profile than MNHO, this advantage weakens with less stringent definitions. Sociodemographic and lifestyle factors strongly modulate atherogenic risk.

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来源期刊
Clinica e Investigacion en Arteriosclerosis
Clinica e Investigacion en Arteriosclerosis PERIPHERAL VASCULAR DISEASE-
CiteScore
3.20
自引率
6.20%
发文量
44
审稿时长
40 days
期刊介绍: La publicación idónea para acceder tanto a los últimos originales de investigación como a formación médica continuada sobre la arteriosclerosis y su etiología, epidemiología, fisiopatología, diagnóstico y tratamiento. Además, es la publicación oficial de la Sociedad Española de Arteriosclerosis.
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