{"title":"术中神经监测结合循证护理对甲状腺癌全甲状腺切除术后患者声带功能、情绪状态、疼痛及生活质量影响的综合研究","authors":"Dandan Chen, Kun Shang","doi":"10.3389/fonc.2025.1611729","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of intraoperative neuromonitoring (IONM) combined with evidence-based nursing on vocal function, emotional status, pain levels, and quality of life (QoL) in patients undergoing total thyroidectomy for thyroid cancer.</p><p><strong>Methods: </strong>A single-center randomized controlled trial was conducted. The intervention group received IONM with evidence-based nursing, while the control group underwent IONM with conventional nursing. Outcomes were assessed using the Hospital Anxiety and Depression Scale (HADS), Numerical Rating Scale (NRS) for pain, EORTC QLQ-C30 for 1-month postoperative QoL, and Voice Handicap Index simplified Chinese version (VHI-10) combined with laryngoscopy for vocal recovery and complications.</p><p><strong>Results: </strong>Compared to controls, the intervention group exhibited significantly lower postoperative VHI-10 scores (5 (2, 8) vs 7 (4, 11), <i>P</i><0.001), reduced HADS anxiety scores (5 (2, 8) vs 10 (4, 12), <i>P</i><0.001), and lower 24-hour NRS pain scores (3 (1, 4) vs 4 (2.75, 4.25), <i>P</i><0.001). The intervention group also demonstrated marked improvements in QLQ-C30 global health status (83 (73.75, 86) vs 77 (72.75, 80), <i>P</i>=0.001), shorter operative duration (92.467 ± 16.916 vs 107.93 ± 24.26 min, <i>P</i><0.001), reduced intraoperative blood loss (16.5 (9.75, 24) vs 23.5 (11.75, 32) mL, <i>P</i>=0.005), and lower postoperative drainage (59 (30, 77.25) vs 82 (46.5, 110.25) mL, <i>P</i>=0.001).</p><p><strong>Conclusion: </strong>The integration of IONM with evidence-based nursing significantly enhanced postoperative recovery and QoL in thyroid cancer patients. Future studies should prioritize larger cohorts, long-term follow-up, and comparisons across surgical techniques to strengthen clinical recommendations. This multimodal approach demonstrates significant potential for optimizing patient-centered outcomes in thyroid surgery.</p>","PeriodicalId":12482,"journal":{"name":"Frontiers in Oncology","volume":"15 ","pages":"1611729"},"PeriodicalIF":3.5000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303996/pdf/","citationCount":"0","resultStr":"{\"title\":\"The impact of intraoperative neuromonitoring combined with evidence-based nursing on vocal cord function, emotional state, pain, and quality of Life in patients after total thyroidectomy for thyroid cancer: a comprehensive study.\",\"authors\":\"Dandan Chen, Kun Shang\",\"doi\":\"10.3389/fonc.2025.1611729\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the impact of intraoperative neuromonitoring (IONM) combined with evidence-based nursing on vocal function, emotional status, pain levels, and quality of life (QoL) in patients undergoing total thyroidectomy for thyroid cancer.</p><p><strong>Methods: </strong>A single-center randomized controlled trial was conducted. The intervention group received IONM with evidence-based nursing, while the control group underwent IONM with conventional nursing. Outcomes were assessed using the Hospital Anxiety and Depression Scale (HADS), Numerical Rating Scale (NRS) for pain, EORTC QLQ-C30 for 1-month postoperative QoL, and Voice Handicap Index simplified Chinese version (VHI-10) combined with laryngoscopy for vocal recovery and complications.</p><p><strong>Results: </strong>Compared to controls, the intervention group exhibited significantly lower postoperative VHI-10 scores (5 (2, 8) vs 7 (4, 11), <i>P</i><0.001), reduced HADS anxiety scores (5 (2, 8) vs 10 (4, 12), <i>P</i><0.001), and lower 24-hour NRS pain scores (3 (1, 4) vs 4 (2.75, 4.25), <i>P</i><0.001). The intervention group also demonstrated marked improvements in QLQ-C30 global health status (83 (73.75, 86) vs 77 (72.75, 80), <i>P</i>=0.001), shorter operative duration (92.467 ± 16.916 vs 107.93 ± 24.26 min, <i>P</i><0.001), reduced intraoperative blood loss (16.5 (9.75, 24) vs 23.5 (11.75, 32) mL, <i>P</i>=0.005), and lower postoperative drainage (59 (30, 77.25) vs 82 (46.5, 110.25) mL, <i>P</i>=0.001).</p><p><strong>Conclusion: </strong>The integration of IONM with evidence-based nursing significantly enhanced postoperative recovery and QoL in thyroid cancer patients. Future studies should prioritize larger cohorts, long-term follow-up, and comparisons across surgical techniques to strengthen clinical recommendations. This multimodal approach demonstrates significant potential for optimizing patient-centered outcomes in thyroid surgery.</p>\",\"PeriodicalId\":12482,\"journal\":{\"name\":\"Frontiers in Oncology\",\"volume\":\"15 \",\"pages\":\"1611729\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303996/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3389/fonc.2025.1611729\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fonc.2025.1611729","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
The impact of intraoperative neuromonitoring combined with evidence-based nursing on vocal cord function, emotional state, pain, and quality of Life in patients after total thyroidectomy for thyroid cancer: a comprehensive study.
Objective: To evaluate the impact of intraoperative neuromonitoring (IONM) combined with evidence-based nursing on vocal function, emotional status, pain levels, and quality of life (QoL) in patients undergoing total thyroidectomy for thyroid cancer.
Methods: A single-center randomized controlled trial was conducted. The intervention group received IONM with evidence-based nursing, while the control group underwent IONM with conventional nursing. Outcomes were assessed using the Hospital Anxiety and Depression Scale (HADS), Numerical Rating Scale (NRS) for pain, EORTC QLQ-C30 for 1-month postoperative QoL, and Voice Handicap Index simplified Chinese version (VHI-10) combined with laryngoscopy for vocal recovery and complications.
Results: Compared to controls, the intervention group exhibited significantly lower postoperative VHI-10 scores (5 (2, 8) vs 7 (4, 11), P<0.001), reduced HADS anxiety scores (5 (2, 8) vs 10 (4, 12), P<0.001), and lower 24-hour NRS pain scores (3 (1, 4) vs 4 (2.75, 4.25), P<0.001). The intervention group also demonstrated marked improvements in QLQ-C30 global health status (83 (73.75, 86) vs 77 (72.75, 80), P=0.001), shorter operative duration (92.467 ± 16.916 vs 107.93 ± 24.26 min, P<0.001), reduced intraoperative blood loss (16.5 (9.75, 24) vs 23.5 (11.75, 32) mL, P=0.005), and lower postoperative drainage (59 (30, 77.25) vs 82 (46.5, 110.25) mL, P=0.001).
Conclusion: The integration of IONM with evidence-based nursing significantly enhanced postoperative recovery and QoL in thyroid cancer patients. Future studies should prioritize larger cohorts, long-term follow-up, and comparisons across surgical techniques to strengthen clinical recommendations. This multimodal approach demonstrates significant potential for optimizing patient-centered outcomes in thyroid surgery.
期刊介绍：
Cancer Imaging and Diagnosis is dedicated to the publication of results from clinical and research studies applied to cancer diagnosis and treatment. The section aims to publish studies from the entire field of cancer imaging: results from routine use of clinical imaging in both radiology and nuclear medicine, results from clinical trials, experimental molecular imaging in humans and small animals, research on new contrast agents in CT, MRI, ultrasound, publication of new technical applications and processing algorithms to improve the standardization of quantitative imaging and image guided interventions for the diagnosis and treatment of cancer.
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