{"title":"一项研究16支细丝牙刷去除牙菌斑效果的随机交叉临床试验","authors":"Nozomi Niki, Makoto Fukui, Ichika Sone, Kosuke Kataoka, Moeno Takeshita, Keisuke Kato, Daisuke Hinode","doi":"10.1002/cre2.70192","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objectives</h3>\n \n <p>Self-care using an appropriate toothbrush is important for oral health management. The aim of this clinical trial in older adults was to evaluate the effectiveness of a prototype toothbrush with 16-branched filament ends (16-BFE) in dental plaque removal compared to a toothbrush with super tapered filament (STF).</p>\n </section>\n \n <section>\n \n <h3> Material and Methods</h3>\n \n <p>Fifty older adults in Japan (13 males and 37 females, mean age 70.8 ± 8.7 years) with 20 or more teeth were enrolled in this study. Participants were divided into Group A (26 subjects) and Group B (24 subjects) and a randomized crossover clinical trial was conducted. Intervention Study I was performed for 3 min using a prototype 16-BFE toothbrush. Dental plaque accumulation areas and gingival abrasion areas were measured before and after brushing by staining with MIRA-2-Ton. Intervention Study II was conducted in the same manner using an STF toothbrush. Crossover design was as follows: Group A was followed by an intervention study from I to II, while Group B was from II to I, with a washout period of 2 or 3 months. Analysis was performed using a modified PCR method (six sections of one tooth surface).</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The average dental plaque removal rate using a 16-BFE toothbrush was 22.4%, which was a significant reduction compared to 18.5% of the STF toothbrush (<i>p</i> < 0.05). There was only one small area out of 1700 areas examined regarding gingival abrasion when using a 16-BFE toothbrush.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>These results suggested that the 16-BFE toothbrush provided a more effective way in dental plaque removal when compared to the STF toothbrush and was less harmful to the gingiva. Even though 16-BFE showed a significant improvement, clinical relevance and long-term effects needed to be further investigated.</p>\n </section>\n </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70192","citationCount":"0","resultStr":"{\"title\":\"A Randomized Crossover Clinical Trial Investigating 16-Branched Filament Toothbrush Effects on Dental Plaque Removal\",\"authors\":\"Nozomi Niki, Makoto Fukui, Ichika Sone, Kosuke Kataoka, Moeno Takeshita, Keisuke Kato, Daisuke Hinode\",\"doi\":\"10.1002/cre2.70192\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>Self-care using an appropriate toothbrush is important for oral health management. The aim of this clinical trial in older adults was to evaluate the effectiveness of a prototype toothbrush with 16-branched filament ends (16-BFE) in dental plaque removal compared to a toothbrush with super tapered filament (STF).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Material and Methods</h3>\\n \\n <p>Fifty older adults in Japan (13 males and 37 females, mean age 70.8 ± 8.7 years) with 20 or more teeth were enrolled in this study. Participants were divided into Group A (26 subjects) and Group B (24 subjects) and a randomized crossover clinical trial was conducted. Intervention Study I was performed for 3 min using a prototype 16-BFE toothbrush. Dental plaque accumulation areas and gingival abrasion areas were measured before and after brushing by staining with MIRA-2-Ton. Intervention Study II was conducted in the same manner using an STF toothbrush. Crossover design was as follows: Group A was followed by an intervention study from I to II, while Group B was from II to I, with a washout period of 2 or 3 months. Analysis was performed using a modified PCR method (six sections of one tooth surface).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The average dental plaque removal rate using a 16-BFE toothbrush was 22.4%, which was a significant reduction compared to 18.5% of the STF toothbrush (<i>p</i> < 0.05). There was only one small area out of 1700 areas examined regarding gingival abrasion when using a 16-BFE toothbrush.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>These results suggested that the 16-BFE toothbrush provided a more effective way in dental plaque removal when compared to the STF toothbrush and was less harmful to the gingiva. Even though 16-BFE showed a significant improvement, clinical relevance and long-term effects needed to be further investigated.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10203,\"journal\":{\"name\":\"Clinical and Experimental Dental Research\",\"volume\":\"11 4\",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70192\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Dental Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/cre2.70192\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Dental Research","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cre2.70192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
A Randomized Crossover Clinical Trial Investigating 16-Branched Filament Toothbrush Effects on Dental Plaque Removal
Objectives
Self-care using an appropriate toothbrush is important for oral health management. The aim of this clinical trial in older adults was to evaluate the effectiveness of a prototype toothbrush with 16-branched filament ends (16-BFE) in dental plaque removal compared to a toothbrush with super tapered filament (STF).
Material and Methods
Fifty older adults in Japan (13 males and 37 females, mean age 70.8 ± 8.7 years) with 20 or more teeth were enrolled in this study. Participants were divided into Group A (26 subjects) and Group B (24 subjects) and a randomized crossover clinical trial was conducted. Intervention Study I was performed for 3 min using a prototype 16-BFE toothbrush. Dental plaque accumulation areas and gingival abrasion areas were measured before and after brushing by staining with MIRA-2-Ton. Intervention Study II was conducted in the same manner using an STF toothbrush. Crossover design was as follows: Group A was followed by an intervention study from I to II, while Group B was from II to I, with a washout period of 2 or 3 months. Analysis was performed using a modified PCR method (six sections of one tooth surface).
Results
The average dental plaque removal rate using a 16-BFE toothbrush was 22.4%, which was a significant reduction compared to 18.5% of the STF toothbrush (p < 0.05). There was only one small area out of 1700 areas examined regarding gingival abrasion when using a 16-BFE toothbrush.
Conclusion
These results suggested that the 16-BFE toothbrush provided a more effective way in dental plaque removal when compared to the STF toothbrush and was less harmful to the gingiva. Even though 16-BFE showed a significant improvement, clinical relevance and long-term effects needed to be further investigated.
期刊介绍：
Clinical and Experimental Dental Research aims to provide open access peer-reviewed publications of high scientific quality representing original clinical, diagnostic or experimental work within all disciplines and fields of oral medicine and dentistry. The scope of Clinical and Experimental Dental Research comprises original research material on the anatomy, physiology and pathology of oro-facial, oro-pharyngeal and maxillofacial tissues, and functions and dysfunctions within the stomatognathic system, and the epidemiology, aetiology, prevention, diagnosis, prognosis and therapy of diseases and conditions that have an effect on the homeostasis of the mouth, jaws, and closely associated structures, as well as the healing and regeneration and the clinical aspects of replacement of hard and soft tissues with biomaterials, and the rehabilitation of stomatognathic functions. Studies that bring new knowledge on how to advance health on the individual or public health levels, including interactions between oral and general health and ill-health are welcome.
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