儿童腹部和盆腔肿瘤:诊断、治疗和预后的综述

V Rudolf von Rohr, M Pachl
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引用次数: 0

摘要

儿童腹部肿瘤虽然相对罕见,但在早期发现、准确诊断和治疗方面存在重大挑战。这些肿瘤是一组异质性的肿瘤,可发生在不同的器官,包括肾脏、肝脏、性腺和软组织,包括一系列良性和恶性的条件。临床表现往往与其他更常见的儿科疾病重叠,使诊断困难,没有高度的怀疑指数。与以恶性为主的成人腹部肿瘤不同,许多儿童腹部肿瘤是良性或低级别恶性肿瘤。然而,恶性肿瘤,如果不治疗或诊断晚,可以显著影响生存。早期干预和多模式治疗策略对于提高生存率和减少长期并发症至关重要。本文综述了神经母细胞瘤、肾母细胞瘤、横纹肌肉瘤、淋巴瘤和卵巢囊肿/生殖细胞瘤等最常见的肿瘤类型。概述将给予临床特点,诊断方法,治疗方案,和预后因素与腹部肿瘤的儿童。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Abdominal and pelvic tumours in children: a review of diagnosis, management, and prognosis
Abdominal tumours in children, though relatively uncommon, present significant challenges in terms of early detection, accurate diagnosis, and treatment. These tumours are a heterogeneous group of neoplasms that can arise from various organs, including the kidneys, liver, gonads and soft tissues, encompassing a range of benign and malignant conditions. The clinical presentation often overlaps with other more common paediatric conditions, making diagnosis difficult without a high index of suspicion. Unlike adult abdominal cancers, which are predominantly malignant, many paediatric abdominal tumours are benign or low-grade malignancies. However, the malignant tumours, if untreated or diagnosed late, can significantly impact survival. Early intervention and multimodal treatment strategies are crucial for improving survival rates and minimizing long-term complications. This review explores the most common types as neuroblastoma, Wilms tumour, rhabdomyosarcoma, lymphoma and ovarian cysts/germ cell tumours. An overview will be given of clinical features, diagnostic approaches, treatment options, and prognostic factors associated with abdominal tumours in children.
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