儿童胃食管反流的外科治疗

Merrill McHoney
{"title":"儿童胃食管反流的外科治疗","authors":"Merrill McHoney","doi":"10.1016/j.mpsur.2025.05.006","DOIUrl":null,"url":null,"abstract":"<div><div>Gastro-oesophageal reflux (GOR) in newborns does not necessarily represent a clinical disease, but rather a somewhat delayed physiological development that corrects with time. Gastro-oesophageal reflux disease (GORD) is defined as secondary symptoms and complications arising from gastro-oesophageal reflux. GORD requires aggressive medical management in an attempt to reverse complications and hopefully achieve long-term cure. Supportive or medical treatment is sufficient in mild cases, but GORD is best managed surgically when severe disease or complications are present. Investigations to support the diagnosis and assess the severity usually include: upper gastrointestinal endoscopy, pH study and upper gastrointestinal contrast study. A combined pH and impedance study may become the gold standard investigative tool with increased experience in children. Surgical procedures for GORD aims to augment or correct some of the mechanisms which prevent GOR. The Nissen fundoplication is the most frequently performed operation, but several other fundoplications are also used. Symptom control can be achieved with improvement in quality of life, but recurrence rates can be high in patients with neurological impairment or generalized bowel dysmotility.</div></div>","PeriodicalId":74889,"journal":{"name":"Surgery (Oxford, Oxfordshire)","volume":"43 8","pages":"Pages 503-509"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Surgical management of gastro-oesophageal reflux in children\",\"authors\":\"Merrill McHoney\",\"doi\":\"10.1016/j.mpsur.2025.05.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Gastro-oesophageal reflux (GOR) in newborns does not necessarily represent a clinical disease, but rather a somewhat delayed physiological development that corrects with time. Gastro-oesophageal reflux disease (GORD) is defined as secondary symptoms and complications arising from gastro-oesophageal reflux. GORD requires aggressive medical management in an attempt to reverse complications and hopefully achieve long-term cure. Supportive or medical treatment is sufficient in mild cases, but GORD is best managed surgically when severe disease or complications are present. Investigations to support the diagnosis and assess the severity usually include: upper gastrointestinal endoscopy, pH study and upper gastrointestinal contrast study. A combined pH and impedance study may become the gold standard investigative tool with increased experience in children. Surgical procedures for GORD aims to augment or correct some of the mechanisms which prevent GOR. The Nissen fundoplication is the most frequently performed operation, but several other fundoplications are also used. Symptom control can be achieved with improvement in quality of life, but recurrence rates can be high in patients with neurological impairment or generalized bowel dysmotility.</div></div>\",\"PeriodicalId\":74889,\"journal\":{\"name\":\"Surgery (Oxford, Oxfordshire)\",\"volume\":\"43 8\",\"pages\":\"Pages 503-509\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgery (Oxford, Oxfordshire)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0263931925000833\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgery (Oxford, Oxfordshire)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0263931925000833","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

新生儿胃食管反流(GOR)并不一定代表一种临床疾病,而是某种程度上延迟的生理发育,随着时间的推移而纠正。胃食管反流病(GORD)被定义为胃食管反流引起的继发症状和并发症。GORD需要积极的医疗管理,以试图逆转并发症,并有望实现长期治愈。在轻度病例中,支持性或药物治疗就足够了,但当出现严重疾病或并发症时,最好进行手术治疗。支持诊断和评估严重程度的检查通常包括:上消化道内镜检查、pH检查和上消化道造影检查。结合pH值和阻抗研究可能成为金标准的调查工具,随着儿童经验的增加。GOR的外科手术旨在增强或纠正一些预防GOR的机制。Nissen底重复是最常执行的操作,但也使用其他几种底重复。症状控制可以通过改善生活质量来实现,但在神经功能障碍或全身性肠蠕动障碍患者中复发率可能很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical management of gastro-oesophageal reflux in children
Gastro-oesophageal reflux (GOR) in newborns does not necessarily represent a clinical disease, but rather a somewhat delayed physiological development that corrects with time. Gastro-oesophageal reflux disease (GORD) is defined as secondary symptoms and complications arising from gastro-oesophageal reflux. GORD requires aggressive medical management in an attempt to reverse complications and hopefully achieve long-term cure. Supportive or medical treatment is sufficient in mild cases, but GORD is best managed surgically when severe disease or complications are present. Investigations to support the diagnosis and assess the severity usually include: upper gastrointestinal endoscopy, pH study and upper gastrointestinal contrast study. A combined pH and impedance study may become the gold standard investigative tool with increased experience in children. Surgical procedures for GORD aims to augment or correct some of the mechanisms which prevent GOR. The Nissen fundoplication is the most frequently performed operation, but several other fundoplications are also used. Symptom control can be achieved with improvement in quality of life, but recurrence rates can be high in patients with neurological impairment or generalized bowel dysmotility.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.00
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信