{"title":"人工智能在胸腔病理学中的诊断和预测应用","authors":"Jan von der Thüsen","doi":"10.1016/j.mpdhp.2025.06.008","DOIUrl":null,"url":null,"abstract":"<div><div>Artificial intelligence (AI) is rapidly transforming thoracic pathology through computational analysis of histological images. This brief review outlines the current state and future directions of clinical AI applications in histopathologic diagnosis of thoracic malignancies, including diagnostic classification, prognosis, prediction of molecular alterations, response to therapy, and assessment of the tumour microenvironment (TME). The technological foundations of AI in pathology are reviewed, highlighting the practical applications and diagnostic challenges in thoracic pathology, as well as issues in interpretability, validation, infrastructure, reimbursement, and regulation.</div></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"31 8","pages":"Pages 486-490"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Artificial intelligence in thoracic pathology: diagnostic and predictive applications\",\"authors\":\"Jan von der Thüsen\",\"doi\":\"10.1016/j.mpdhp.2025.06.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Artificial intelligence (AI) is rapidly transforming thoracic pathology through computational analysis of histological images. This brief review outlines the current state and future directions of clinical AI applications in histopathologic diagnosis of thoracic malignancies, including diagnostic classification, prognosis, prediction of molecular alterations, response to therapy, and assessment of the tumour microenvironment (TME). The technological foundations of AI in pathology are reviewed, highlighting the practical applications and diagnostic challenges in thoracic pathology, as well as issues in interpretability, validation, infrastructure, reimbursement, and regulation.</div></div>\",\"PeriodicalId\":39961,\"journal\":{\"name\":\"Diagnostic Histopathology\",\"volume\":\"31 8\",\"pages\":\"Pages 486-490\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic Histopathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1756231725001124\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231725001124","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Artificial intelligence in thoracic pathology: diagnostic and predictive applications
Artificial intelligence (AI) is rapidly transforming thoracic pathology through computational analysis of histological images. This brief review outlines the current state and future directions of clinical AI applications in histopathologic diagnosis of thoracic malignancies, including diagnostic classification, prognosis, prediction of molecular alterations, response to therapy, and assessment of the tumour microenvironment (TME). The technological foundations of AI in pathology are reviewed, highlighting the practical applications and diagnostic challenges in thoracic pathology, as well as issues in interpretability, validation, infrastructure, reimbursement, and regulation.
期刊介绍:
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.