1990年至2021年全球、区域和国家区域育龄妇女高血压心脏病负担及2040年预测

IF 2.4 Q2 OBSTETRICS & GYNECOLOGY
Frontiers in global women's health Pub Date : 2025-07-11 eCollection Date: 2025-01-01 DOI:10.3389/fgwh.2025.1600340
Zhenglong Wang, Hao Li, Hongwei Wei, Baotang Liu, Lei Li, Zijun Li, Jindong Feng, Yunjie Hu, Xiaobo Liu
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引用次数: 0

摘要

背景:本研究的重点是阐明育龄妇女高血压心脏病(HHD)的全球负担。本研究利用所有可用数据,采用全球疾病负担(GBD)研究的方法,旨在全面分析这种高流行疾病的流行病学特征。方法:在本研究中,我们从GBD数据库中检索了1990年至2021年期间WCBA中与HHD相关的患病率、发病率和dalys三个关键指标。我们的研究提供了点估计及其相应的95%不确定区间(ui)。使用EAPC和百分比变化来评估演变趋势。结果:2021年,WCBA中HHD的全球患病率为544,544例,导致25,669例死亡。与1990年相比,患病率增加了110%,死亡率增加了27%。从1990年到2021年,患病率呈上升趋势(EAPC: 1.31),而死亡率呈下降趋势(EAPC: -0.51)。2021年,中等SDI区域的患病率最高(30.88 / 10万),而低SDI区域的死亡率最高(2.44 / 10万),DALYs负担最重(125.39 / 10万)。2021年,在不同年龄组中,45-49岁年龄组的病例数最多(195288例),患病率最高(82.87 / 10万)。此外,HHD患病率与年龄呈正相关。结论:总体而言,在全球范围内,WCBA的HHD负担在过去32年中显著增加。这一趋势在低SDI地区和45-49岁年龄组尤为明显。这项研究的结果强调了有针对性的干预措施解决这一问题的迫切需要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040.

Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040.

Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040.

Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040.

Background: The present research focuses on elucidating the global burden of hypertensive heart disease (HHD) among women of childbearing age (WCBA). By utilizing all available data and adopting the methodology employed in the Global Burden of Disease (GBD) study, this study aims to comprehensively analyze the epidemiological characteristics of this highly prevalent disorder.

Methods: In this research, we retrieved three key indicators-prevalence, incidence, and DALYs-related to HHD in WCBA from the GBD database for the period 1990 to 2021. Our study provides point estimates along with their corresponding 95% uncertainty intervals (UIs). The evolving trends were assessed using the EAPC and percentage change.

Results: In 2021, the global prevalence of HHD among WCBA was 544,544 cases, resulting in 25,669 deaths. Compared to 1990, the prevalence increased by 110%, and mortality rose by 27%. From 1990 to 2021, the prevalence rate showed an upward trend (EAPC: 1.31), whereas the mortality rate exhibited a decline (EAPC: -0.51). In 2021, middle SDI regions recorded the highest prevalence rate (30.88 per 100,000), while low SDI regions had the highest mortality rate (2.44 per 100,000) and the greatest burden of DALYs (125.39 per 100,000). Among different age groups in 2021, the 45-49 age group experienced the highest number of cases (195,288) and the highest prevalence rate (82.87 per 100,000). Furthermore, HHD prevalence demonstrated a positive correlation with age.

Conclusion: Overall, on a global scale, the burden of HHD among WCBA has significantly increased over the past 32 years. This trend is particularly pronounced in low SDI regions and within the 45-49 age group. The findings of this study highlight the critical need for targeted interventions to address this issue.

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