Qian Wang, Jinmeng Ni, Yongyi Guan, Xiaolin Liu, Meng Li, Hui Xue, Wei Du, Lijun Fan
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Associations of Depression and Symptomatic Knee Osteoarthritis with Cognitive Function Among Middle-Aged and Older Adults: Evidence from CHARLS in China.
This study investigated the separate and joint relationships of depression and symptomatic knee osteoarthritis (KOA) with cognitive function among 11,645 Chinese adults aged 45 or above from the China Health and Retirement Longitudinal Study (CHARLS, 2011-2020). We found that both conditions were individually associated with poorer cognition (all β < 0; all p < .01). Depression, alone or with KOA, consistently demonstrated lower global and subdomain-specific cognitive scores (all β < 0; all p < .001). Comorbid depression and KOA generally exerted greater negative impact on cognition than either condition alone. Our findings highlight early screening and holistic, rather than single-disease, care approaches.
期刊介绍:
With over 30 years of consistent, quality articles devoted to social work practice, theory, administration, and consultation in the field of aging, the Journal of Gerontological Social Work offers you the information you need to stay abreast of the changing and controversial issues of today"s growing aging population. A valuable resource for social work administrators, practitioners, consultants, and supervisors in long-term care facilities, acute treatment and psychiatric hospitals, mental health centers, family service agencies, community and senior citizen centers, and public health and welfare agencies, JGSW provides a respected and stable forum for cutting-edge insights by experts in the field.