Bramasto Purbo Sejati, Ahmad Kusumaatmaja, Maria Goreti Widiastuti, Tetiana Haniastuti
{"title":"应用于颌面外科的微型钛板生物膜形成的临床和显微证据:一个病例系列分析。","authors":"Bramasto Purbo Sejati, Ahmad Kusumaatmaja, Maria Goreti Widiastuti, Tetiana Haniastuti","doi":"10.1080/23320885.2025.2535707","DOIUrl":null,"url":null,"abstract":"<p><p>Titanium miniplates, though biocompatible, often require removal due to infections (3-18%), primarily from Staphylococcus aureus. Biofilms, which resist antibiotics, drive persistent infections. We analyzed 10 infected miniplates via SEM, revealing dense polymicrobial biofilms, especially near screw holes. These structured microbial communities underscore the need for biofilm-targeted treatments to improve outcomes.</p>","PeriodicalId":42421,"journal":{"name":"Case Reports in Plastic Surgery and Hand Surgery","volume":"12 1","pages":"2535707"},"PeriodicalIF":0.6000,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12302400/pdf/","citationCount":"0","resultStr":"{\"title\":\"Clinical and microscopic evidence of biofilm formation on titanium miniplates applied in maxillofacial surgery: a case series analysis.\",\"authors\":\"Bramasto Purbo Sejati, Ahmad Kusumaatmaja, Maria Goreti Widiastuti, Tetiana Haniastuti\",\"doi\":\"10.1080/23320885.2025.2535707\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Titanium miniplates, though biocompatible, often require removal due to infections (3-18%), primarily from Staphylococcus aureus. Biofilms, which resist antibiotics, drive persistent infections. We analyzed 10 infected miniplates via SEM, revealing dense polymicrobial biofilms, especially near screw holes. These structured microbial communities underscore the need for biofilm-targeted treatments to improve outcomes.</p>\",\"PeriodicalId\":42421,\"journal\":{\"name\":\"Case Reports in Plastic Surgery and Hand Surgery\",\"volume\":\"12 1\",\"pages\":\"2535707\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-07-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12302400/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Plastic Surgery and Hand Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/23320885.2025.2535707\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Plastic Surgery and Hand Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/23320885.2025.2535707","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}
Clinical and microscopic evidence of biofilm formation on titanium miniplates applied in maxillofacial surgery: a case series analysis.
Titanium miniplates, though biocompatible, often require removal due to infections (3-18%), primarily from Staphylococcus aureus. Biofilms, which resist antibiotics, drive persistent infections. We analyzed 10 infected miniplates via SEM, revealing dense polymicrobial biofilms, especially near screw holes. These structured microbial communities underscore the need for biofilm-targeted treatments to improve outcomes.