改良简单角膜缘上皮移植治疗猫眼睑粘连的初步研究。

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES
Veterinary ophthalmology Pub Date : 2026-03-01 Epub Date: 2025-07-28 DOI:10.1111/vop.70051
William Irving, Emily Perry, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Cameron Whittaker, Matthew Annear
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引用次数: 0

摘要

目的:介绍一种改良的单纯角膜缘上皮移植治疗角膜结膜粘连的手术方法。方法:对4只猫进行了对侧正常眼到受体眼的自体改良SLET移植。根据角膜受影响程度和角膜清晰度对患者术前和术后进行评分。结果:4例患者中有3例患者的角膜清晰度评分和结膜占用的角膜面积均有明显改善。一例患者术后1个月出现角膜感染,角膜清晰度改善甚微。结论:自体角膜缘移植是治疗单侧猫角膜结膜粘连的有效方法。与已发表的单纯手术切除的结果相比,角膜缘移植可以提高角膜清晰度,减少受睑粘连影响的角膜。进一步的研究是必要的,以完善程序,并确定同种异体移植是否有效的情况下,双侧睑粘连。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modified Simple Limbal Epithelial Transplant for the Treatment of Symblepharon in Cats: A Pilot Study.

Purpose: To describe a surgical technique to treat keratoconjunctival symblepharon with a modified simple limbal epithelial transplant (SLET).

Methods: Four cats underwent an autologous modified SLET from a normal contralateral eye to the recipient eye. Patients were scored preoperatively and postoperatively based on the degree of cornea affected and the corneal clarity.

Results: Three of the four cases had significant improvements in both their corneal clarity scores and the amount of cornea occupied by conjunctiva. One case developed a corneal infection in the recipient eye 1 month postoperatively, with minimal improvements being made to the corneal clarity.

Conclusions: This study suggests that autologous limbal transplants can be an effective surgical treatment for unilateral feline keratoconjunctival symblepharon. Compared to published results of surgical removal alone, limbal transplants can result in more corneal clarity and less cornea affected by symblepharon. Further investigation is warranted to refine the procedure as well as determine whether allogenic transplantation is effective in cases of bilateral symblepharon.

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来源期刊
Veterinary ophthalmology
Veterinary ophthalmology 农林科学-兽医学
CiteScore
2.70
自引率
37.50%
发文量
82
审稿时长
12-24 weeks
期刊介绍: Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.
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