William Irving, Emily Perry, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Cameron Whittaker, Matthew Annear
{"title":"改良简单角膜缘上皮移植治疗猫眼睑粘连的初步研究。","authors":"William Irving, Emily Perry, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Cameron Whittaker, Matthew Annear","doi":"10.1111/vop.70051","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To describe a surgical technique to treat keratoconjunctival symblepharon with a modified simple limbal epithelial transplant (SLET).</p><p><strong>Methods: </strong>Four cats underwent an autologous modified SLET from a normal contralateral eye to the recipient eye. Patients were scored preoperatively and postoperatively based on the degree of cornea affected and the corneal clarity.</p><p><strong>Results: </strong>Three of the four cases had significant improvements in both their corneal clarity scores and the amount of cornea occupied by conjunctiva. One case developed a corneal infection in the recipient eye 1 month postoperatively, with minimal improvements being made to the corneal clarity.</p><p><strong>Conclusions: </strong>This study suggests that autologous limbal transplants can be an effective surgical treatment for unilateral feline keratoconjunctival symblepharon. Compared to published results of surgical removal alone, limbal transplants can result in more corneal clarity and less cornea affected by symblepharon. Further investigation is warranted to refine the procedure as well as determine whether allogenic transplantation is effective in cases of bilateral symblepharon.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":"e70051"},"PeriodicalIF":1.3000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modified Simple Limbal Epithelial Transplant for the Treatment of Symblepharon in Cats: A Pilot Study.\",\"authors\":\"William Irving, Emily Perry, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Cameron Whittaker, Matthew Annear\",\"doi\":\"10.1111/vop.70051\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To describe a surgical technique to treat keratoconjunctival symblepharon with a modified simple limbal epithelial transplant (SLET).</p><p><strong>Methods: </strong>Four cats underwent an autologous modified SLET from a normal contralateral eye to the recipient eye. Patients were scored preoperatively and postoperatively based on the degree of cornea affected and the corneal clarity.</p><p><strong>Results: </strong>Three of the four cases had significant improvements in both their corneal clarity scores and the amount of cornea occupied by conjunctiva. One case developed a corneal infection in the recipient eye 1 month postoperatively, with minimal improvements being made to the corneal clarity.</p><p><strong>Conclusions: </strong>This study suggests that autologous limbal transplants can be an effective surgical treatment for unilateral feline keratoconjunctival symblepharon. Compared to published results of surgical removal alone, limbal transplants can result in more corneal clarity and less cornea affected by symblepharon. Further investigation is warranted to refine the procedure as well as determine whether allogenic transplantation is effective in cases of bilateral symblepharon.</p>\",\"PeriodicalId\":23836,\"journal\":{\"name\":\"Veterinary ophthalmology\",\"volume\":\" \",\"pages\":\"e70051\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2026-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary ophthalmology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1111/vop.70051\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary ophthalmology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1111/vop.70051","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/28 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Modified Simple Limbal Epithelial Transplant for the Treatment of Symblepharon in Cats: A Pilot Study.
Purpose: To describe a surgical technique to treat keratoconjunctival symblepharon with a modified simple limbal epithelial transplant (SLET).
Methods: Four cats underwent an autologous modified SLET from a normal contralateral eye to the recipient eye. Patients were scored preoperatively and postoperatively based on the degree of cornea affected and the corneal clarity.
Results: Three of the four cases had significant improvements in both their corneal clarity scores and the amount of cornea occupied by conjunctiva. One case developed a corneal infection in the recipient eye 1 month postoperatively, with minimal improvements being made to the corneal clarity.
Conclusions: This study suggests that autologous limbal transplants can be an effective surgical treatment for unilateral feline keratoconjunctival symblepharon. Compared to published results of surgical removal alone, limbal transplants can result in more corneal clarity and less cornea affected by symblepharon. Further investigation is warranted to refine the procedure as well as determine whether allogenic transplantation is effective in cases of bilateral symblepharon.
期刊介绍:
Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of:
Clinical and investigational veterinary and comparative ophthalmology;
Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species;
Experimental models of both animal and human ocular disease in veterinary species;
Anatomic studies of the animal eye;
Physiological studies of the animal eye;
Pharmacological studies of the animal eye.