建立一个模型来指导左侧乳腺癌患者深度吸气屏气的放疗决策。

IF 2.5 3区医学 Q3 ONCOLOGY

Strahlentherapie und Onkologie Pub Date : 2025-07-29 DOI:10.1007/s00066-025-02438-4

Annett Linge, Carina Ketzmerick, Kristin Gurtner, Cordelia Hoinkis, Steffen Löck, Mechthild Krause

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引用次数: 0

摘要

接受放射治疗的左侧乳腺癌患者有发生慢性心脏毒性的风险。心脏剂量节约技术，如深吸气屏气（DIBH）可以降低这种风险。本研究建立了肿瘤定位、左肺体积、心脏与胸壁内侧距离、年龄和东部肿瘤合作组（ECOG）表现状态的模型，有助于在放疗计划开始前直接规划自由呼吸CT扫描后决定是否进行DIBH。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Development of a model to guide the decision for radiotherapy in deep-inspiration breath-hold in patients with left-sided breast cancer.

Patients with left-sided breast cancer receiving radiotherapy are at risk of developing chronic cardiac toxicities. Cardiac dose-sparing techniques such as deep-inspiration breath-hold (DIBH) can reduce this risk. In this study, a model has been developed including tumor localization, left lung volume, and the distance between the heart and medial chest wall as well as age and Eastern Cooperative Oncology Group (ECOG) performance status, which may help to guide the decision for or against DIBH after planning computed tomography (CT) in free breathing directly before initiation of radiotherapy planning.

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来源期刊

Strahlentherapie und Onkologie 医学-核医学

CiteScore

5.70

自引率

12.90%

发文量

141

审稿时长

3-8 weeks

期刊介绍： Strahlentherapie und Onkologie, published monthly, is a scientific journal that covers all aspects of oncology with focus on radiooncology, radiation biology and radiation physics. The articles are not only of interest to radiooncologists but to all physicians interested in oncology, to radiation biologists and radiation physicists. The journal publishes original articles, review articles and case studies that are peer-reviewed. It includes scientific short communications as well as a literature review with annotated articles that inform the reader on new developments in the various disciplines concerned and hence allow for a sound overview on the latest results in radiooncology research. Founded in 1912, Strahlentherapie und Onkologie is the oldest oncological journal in the world. Today, contributions are published in English and German. All articles have English summaries and legends. The journal is the official publication of several scientific radiooncological societies and publishes the relevant communications of these societies.