Dhuha Jalil Lawi, Iman Sabah Obaid, Ali Abid Abojassim, Abdulhussein Abdulameer Alkufi
{"title":"伊拉克纳杰夫省肺癌患者的氡浓度和CBC参数。","authors":"Dhuha Jalil Lawi, Iman Sabah Obaid, Ali Abid Abojassim, Abdulhussein Abdulameer Alkufi","doi":"10.1007/s00411-025-01139-x","DOIUrl":null,"url":null,"abstract":"<p><p>The research described in this paper aimed to identify <sup>222</sup>Rn concentrations in the serum of healthy individuals and lung cancer patients. Additionally, CBC parameters such as WBC (White Blood Cell count), RBC (Red Blood Cells), MCH (Mean Corpuscular Hemoglobin), and PLT (Platelets) were measured and their correlation with the corresponding <sup>222</sup>Rn concentrations in the serum of the lung cancer patients was investigated. <sup>222</sup>Rn concentrations in serum samples were measured using a CR-39 detector. The mean <sup>222</sup>Rn concentration in the serum of the patients was 22.62 ± 3.85 Bq/m<sup>3</sup>, while that in serum of the healthy individuals was 2.72 ± 0.71 Bq/m<sup>3</sup>. Also, it was found that the mean WBC, RBC, MCH, and PLT levels in the serum of the patients were 7.15 ± 0.58 cells/L, 4.24 ± 0.17 cells/L, 29.23 ± 0.60 pg, and 285.52 ± 21.78 cells/L, respectively. The results revealed statistically significant differences in <sup>222</sup>Rn concentrations when comparing the samples of the patients with those of the healthy individuals. In addition, a reasonable correlation was found (p < 0.01) between the <sup>222</sup>Rn concentrations and MCH levels in serum of the patients. It is concluded that, given the observed correlations, further studies are necessary to investigate whether there is any causal relationship behind the observed correlations.</p>","PeriodicalId":21002,"journal":{"name":"Radiation and Environmental Biophysics","volume":" ","pages":"477-485"},"PeriodicalIF":2.3000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Radon concentrations and CBC parameters in lung cancer patients at Al-Najaf governorate, Iraq.\",\"authors\":\"Dhuha Jalil Lawi, Iman Sabah Obaid, Ali Abid Abojassim, Abdulhussein Abdulameer Alkufi\",\"doi\":\"10.1007/s00411-025-01139-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The research described in this paper aimed to identify <sup>222</sup>Rn concentrations in the serum of healthy individuals and lung cancer patients. Additionally, CBC parameters such as WBC (White Blood Cell count), RBC (Red Blood Cells), MCH (Mean Corpuscular Hemoglobin), and PLT (Platelets) were measured and their correlation with the corresponding <sup>222</sup>Rn concentrations in the serum of the lung cancer patients was investigated. <sup>222</sup>Rn concentrations in serum samples were measured using a CR-39 detector. The mean <sup>222</sup>Rn concentration in the serum of the patients was 22.62 ± 3.85 Bq/m<sup>3</sup>, while that in serum of the healthy individuals was 2.72 ± 0.71 Bq/m<sup>3</sup>. Also, it was found that the mean WBC, RBC, MCH, and PLT levels in the serum of the patients were 7.15 ± 0.58 cells/L, 4.24 ± 0.17 cells/L, 29.23 ± 0.60 pg, and 285.52 ± 21.78 cells/L, respectively. The results revealed statistically significant differences in <sup>222</sup>Rn concentrations when comparing the samples of the patients with those of the healthy individuals. In addition, a reasonable correlation was found (p < 0.01) between the <sup>222</sup>Rn concentrations and MCH levels in serum of the patients. It is concluded that, given the observed correlations, further studies are necessary to investigate whether there is any causal relationship behind the observed correlations.</p>\",\"PeriodicalId\":21002,\"journal\":{\"name\":\"Radiation and Environmental Biophysics\",\"volume\":\" \",\"pages\":\"477-485\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiation and Environmental Biophysics\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://doi.org/10.1007/s00411-025-01139-x\",\"RegionNum\":4,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/29 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation and Environmental Biophysics","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1007/s00411-025-01139-x","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/29 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
Radon concentrations and CBC parameters in lung cancer patients at Al-Najaf governorate, Iraq.
The research described in this paper aimed to identify 222Rn concentrations in the serum of healthy individuals and lung cancer patients. Additionally, CBC parameters such as WBC (White Blood Cell count), RBC (Red Blood Cells), MCH (Mean Corpuscular Hemoglobin), and PLT (Platelets) were measured and their correlation with the corresponding 222Rn concentrations in the serum of the lung cancer patients was investigated. 222Rn concentrations in serum samples were measured using a CR-39 detector. The mean 222Rn concentration in the serum of the patients was 22.62 ± 3.85 Bq/m3, while that in serum of the healthy individuals was 2.72 ± 0.71 Bq/m3. Also, it was found that the mean WBC, RBC, MCH, and PLT levels in the serum of the patients were 7.15 ± 0.58 cells/L, 4.24 ± 0.17 cells/L, 29.23 ± 0.60 pg, and 285.52 ± 21.78 cells/L, respectively. The results revealed statistically significant differences in 222Rn concentrations when comparing the samples of the patients with those of the healthy individuals. In addition, a reasonable correlation was found (p < 0.01) between the 222Rn concentrations and MCH levels in serum of the patients. It is concluded that, given the observed correlations, further studies are necessary to investigate whether there is any causal relationship behind the observed correlations.
期刊介绍:
This journal is devoted to fundamental and applied issues in radiation research and biophysics. The topics may include:
Biophysics of ionizing radiation: radiation physics and chemistry, radiation dosimetry, radiobiology, radioecology, biophysical foundations of medical applications of radiation, and radiation protection.
Biological effects of radiation: experimental or theoretical work on molecular or cellular effects; relevance of biological effects for risk assessment; biological effects of medical applications of radiation; relevance of radiation for biosphere and in space; modelling of ecosystems; modelling of transport processes of substances in biotic systems.
Risk assessment: epidemiological studies of cancer and non-cancer effects; quantification of risk including exposures to radiation and confounding factors
Contributions to these topics may include theoretical-mathematical and experimental material, as well as description of new techniques relevant for the study of these issues. They can range from complex radiobiological phenomena to issues in health physics and environmental protection.