Jinya Lin, Rending Wang, Yuanyuan Zhu, Weijia Huang, Jie Sun
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引用次数: 0
摘要
嗜酸性肉芽肿病合并多血管炎(EGPA)是一种罕见的多系统疾病,由于其复杂性和低发病率,给诊断带来了重大挑战(White和Dubey, 2023)。它对男性和女性的影响相同,尽管男性在诊断时可能表现出更活跃的疾病,通常需要更积极的治疗(Liu et al., 2023)。EGPA的标志性特征包括迟发性哮喘、组织和血液嗜酸性粒细胞增加以及影响中小动脉的血管炎(White和Dubey, 2023)。EGPA属于抗中性粒细胞胞浆抗体(ANCA)相关血管炎(AAV)的范畴,而只有大约一半的EGPA患者检测出ANCA阳性(Khoury等人,2023)。
A case of cardiac arrest and spontaneous renal hemorrhage in a male patient with persistent eosinophilia: highlighting the importance of early diagnosis of eosinophilic granulomatosis with polyangiitis.
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multi-system disease that presents significant diagnostic challenges due to its complexity and low incidence (White and Dubey, 2023). It affects males and females equally, though males may exhibit more active disease at diagnosis and often require more aggressive treatment (Liu et al., 2023). The hallmark features of EGPA include delayed-onset asthma, eosinophilia in tissues and blood, and vasculitis affecting small to medium-sized arteries (White and Dubey, 2023). EGPA falls under the category of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), whereas only about half of EGPA patients test positive for ANCA (Khoury et al., 2023).
期刊介绍:
Journal of Zheijang University SCIENCE B - Biomedicine & Biotechnology is an international journal that aims to present the latest development and achievements in scientific research in China and abroad to the world’s scientific community.
JZUS-B covers research in Biomedicine and Biotechnology and Biochemistry and topics related to life science subjects, such as Plant and Animal Sciences, Environment and Resource etc.