半关节置换术轴承材料的体外评价:范围综述(第一部分)。

IF 2.3 3区 医学 Q2 ORTHOPEDICS
Victoria P Marino, Francesca De Vecchi, Takayuki Koya, Landon M Begin, Douglas C Moore, Joseph J Crisco, Markus A Wimmer
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引用次数: 0

摘要

半关节成形术用于治疗局限于一侧的关节损伤,旨在保护剩余的健康软骨和骨骼,同时解决股骨骨折和骨坏死等疾病;然而,由于软骨磨损和不一致的临床结果,挑战仍然存在。本综述评估了半关节置换术轴承材料(HBM)的体外研究,重点是HBM测试、软骨标本、实验设置、结果变量和结果的可比性。在1798项已确定的研究中,72项符合纳入标准,其中48项被归类为体外研究。测试的HBMs包括金属(42%)和软聚合物(30%),45%的研究使用了多种不同的HBMs。软骨标本主要是牛(65%),主要来自胫骨-股关节(69%)。两种最常见的实验装置是摩擦计(75%)和模拟器(25%),它们都使用商用和定制的钻机。摩擦计的配置包括针对盘和针对板模型和模拟器突出球对关节设置。摩擦计的运动包括线性往复运动(62%)或多向往复运动(24%)。输入参数包括接触应力(8.8 kPa ~ 23.3 MPa,平均2.1 MPa)、速度(0.5 ~ 100 mm/s,平均16.46 mm/s)、测试时间(0.03 ~ 33.8 h,平均5.4 h)和距离(5.4 cm ~ 9000 m,平均393 m)。模拟器使用的输入载荷范围从25n到1.5 kN, 500到500,000次循环,以及各种屈伸轮廓和二次运动。润滑剂主要是牛血清(38%)和盐基溶液(21%)。结果变量主要包括摩擦系数、软骨和/或HBM损伤,但评估这些结果的方法各不相同。方法上的差异和不一致的结果报告限制了对HBMs相对表现得出确切结论的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I).

Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes. This scoping review evaluates in vitro studies on hemiarthroplasty bearing materials (HBM), focusing on the HBM tested, cartilage specimens, experimental setups, outcome variables, and the comparability of results. Of 1798 identified studies, 72 met the inclusion criteria, with 48 classified as in vitro. HBMs tested included metals (42%) and soft polymers (30%) and 45% of studies utilized multiple distinct HBMs. Cartilage specimens were predominantly bovine (65%), mostly from the tibial-femoral joint (69%). The two most common experimental set ups were tribometers (75%) and simulators (25%) both using commercial and custom-built rigs. Tribometer configurations included pin-on-disc and pin-on-plate models and simulators highlighted ball-on-joint set ups. Tribometer motions included linear reciprocating (62%) or multidirectional reciprocating (24%). Input parameters included contact stress (8.8 kPa to 23.3 MPa, mean 2.1 MPa), velocity (0.5-100 mm/s, mean 16.46 mm/s), testing duration (0.03-33.8 h, mean 5.4 h), and distance (5.4 cm to 9000 m, mean 393 m). Simulators used inputs of loads ranging from 25 N to 1.5 kN, 500 to 500,000 cycles and a variety of flexion-extension profiles together with secondary motions. Lubricants were mostly bovine calf serum (38%) and saline-based solutions (21%). Outcome variables mainly included coefficient of friction and damage to cartilage and/or HBM, but the methods to assess these outputs varied. Methodological differences and inconsistent reporting of outcomes limited the ability to draw firm conclusions about the relative performance of HBMs.

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来源期刊
Journal of Orthopaedic Research®
Journal of Orthopaedic Research® 医学-整形外科
CiteScore
6.10
自引率
3.60%
发文量
261
审稿时长
3-6 weeks
期刊介绍: The Journal of Orthopaedic Research is the forum for the rapid publication of high quality reports of new information on the full spectrum of orthopaedic research, including life sciences, engineering, translational, and clinical studies.
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