Mohammad Mohajeri, Reza Momenai, Somayyeh Karami-Mohajeri, Mandana Ohadi, Mohammad Amin Raeisi Estabragh
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Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of Action.
Context: Curcumin, a natural compound derived from the rhizome of the turmeric plant, exhibits various pharmacological and therapeutic effects through distinct cellular and molecular mechanisms.
Evidence acquisition: Given the therapeutic applications and pharmacological properties of curcumin, it is essential to explore its pharmacological effects for potential use in clinical research. Notably, curcumin demonstrates significant antioxidant, anti-inflammatory, and anti-cancer properties. Importantly, no side effects or specific toxicity have been reported for curcumin.
Results: Curcumin, as a natural compound, can be utilized as a drug supplement in treatment regimens for various diseases. Numerous clinical studies have indicated that curcumin enhances the efficacy of chemotherapy drugs or mitigates their side effects when used concurrently.
Conclusions: This review presents an overview of studies conducted on the pharmacological effects and therapeutic properties of curcumin.
期刊介绍:
The Iranian Journal of Pharmaceutical Research (IJPR) is a peer-reviewed multi-disciplinary pharmaceutical publication, scheduled to appear quarterly and serve as a means for scientific information exchange in the international pharmaceutical forum. Specific scientific topics of interest to the journal include, but are not limited to: pharmaceutics, industrial pharmacy, pharmacognosy, toxicology, medicinal chemistry, novel analytical methods for drug characterization, computational and modeling approaches to drug design, bio-medical experience, clinical investigation, rational drug prescribing, pharmacoeconomics, biotechnology, nanotechnology, biopharmaceutics and physical pharmacy.