{"title":"医学罕见:免疫正常患者脑垂体分离弓形虫脓肿。","authors":"Erlend Moen Taule, Hrvoje Miletic, Rupavathana Mahesparan","doi":"10.1155/crdi/9943637","DOIUrl":null,"url":null,"abstract":"<p><p>The occurrence of sellar toxoplasmosis in the pituitary gland is exceedingly rare, and only a few reports have been published in the literature, primarily impacting immunocompromised patients. We report an intriguing case of a 54-year-old man with an initial asymptomatic panhypopituitarism diagnosed under investigation for urolithiasis. Cranial CT and MRI revealed a large sellar lesion first suspectable of a nonfunctioning pituitary macroadenoma. An endonasal transsphenoidal surgery was performed, and the histopathological diagnosis was surprisingly a pituitary <i>Toxoplasma gondii</i> abscess. This case highlights that these types of infections can also occur in immunocompetent patients.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2025 ","pages":"9943637"},"PeriodicalIF":0.8000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303648/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Medical Rarity: Isolated <i>Toxoplasma gondii</i> Abscess in the Pituitary Gland of an Immunocompetent Patient.\",\"authors\":\"Erlend Moen Taule, Hrvoje Miletic, Rupavathana Mahesparan\",\"doi\":\"10.1155/crdi/9943637\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The occurrence of sellar toxoplasmosis in the pituitary gland is exceedingly rare, and only a few reports have been published in the literature, primarily impacting immunocompromised patients. We report an intriguing case of a 54-year-old man with an initial asymptomatic panhypopituitarism diagnosed under investigation for urolithiasis. Cranial CT and MRI revealed a large sellar lesion first suspectable of a nonfunctioning pituitary macroadenoma. An endonasal transsphenoidal surgery was performed, and the histopathological diagnosis was surprisingly a pituitary <i>Toxoplasma gondii</i> abscess. This case highlights that these types of infections can also occur in immunocompetent patients.</p>\",\"PeriodicalId\":9608,\"journal\":{\"name\":\"Case Reports in Infectious Diseases\",\"volume\":\"2025 \",\"pages\":\"9943637\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303648/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Infectious Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crdi/9943637\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crdi/9943637","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
A Medical Rarity: Isolated Toxoplasma gondii Abscess in the Pituitary Gland of an Immunocompetent Patient.
The occurrence of sellar toxoplasmosis in the pituitary gland is exceedingly rare, and only a few reports have been published in the literature, primarily impacting immunocompromised patients. We report an intriguing case of a 54-year-old man with an initial asymptomatic panhypopituitarism diagnosed under investigation for urolithiasis. Cranial CT and MRI revealed a large sellar lesion first suspectable of a nonfunctioning pituitary macroadenoma. An endonasal transsphenoidal surgery was performed, and the histopathological diagnosis was surprisingly a pituitary Toxoplasma gondii abscess. This case highlights that these types of infections can also occur in immunocompetent patients.