{"title":"使用哈萨克语版“皮肤病生活质量指数”问卷评估特应性皮炎患者的生活质量。","authors":"Gulya Sarybayeva, Ulzhan Beisebayeva, Leila Almenova, Askar Khabizhanov, Saniya Ospanova, Dinara Rysbekova, Zhanat Ispayeva, Shynar Tanabayeva, Timur Saliev, Ildar Fakhradiyev","doi":"10.5415/apallergy.0000000000000183","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The effectiveness of the Dermatology Life Quality Index (DLQI), translated into Kazakh, for assessing the quality of life of patients with atopic dermatitis (AD) in Kazakhstan, has not yet been evaluated.</p><p><strong>Objective: </strong>The aim of the study is to assess the reliability and validity of the Kazakh language DLQI as a tool for assessing the quality of life of patients with AD.</p><p><strong>Methods: </strong>This multicenter study involved 883 adult patients of the Kazakh population diagnosed with AD. To assess the quality of life of AD patients, the DLQI questionnaire translated into Kazakh was used.</p><p><strong>Results: </strong>The reliability (Cronbach <i>α</i>) of the Kazakh version DLQI questionnaire was -0.924. The average DLQI score for the sample was 10.7 ± 8.2. Nearly 53.8% of patients had mild AD and 35.3% had moderate AD. According to the DLQI questionnaire, the average score increases with rising body mass index: patients who are overweight (11.9 ± 8.5) and those with obesity of the first degree (13.1 ± 9.0) have scores indicating a significant impact of the skin disease on their quality of life, whereas patients with normal weight (10.2 ± 8.0) or underweight (7.9 ± 7.4) experienced a more moderate effect, <i>P</i> = 0.001. Relapses 2 times a year (12.2 ± 8.5) and 3 or more times a year (12.6 ± 8.7) worsened the quality of life relatively more than relapses 1 time per year, <i>P</i> = 0.001. Smoking and alcohol consumption affected the deterioration in the quality of life of patients with AD (<i>P</i> ≤ 0.05). The quality of life of patients with AD in remission according to the DLQI scale was higher, <i>P</i> = 0.001.</p><p><strong>Conclusion: </strong>The results demonstrate that the Kazakh language version of the DLQI is a reliable and valid tool for measuring the impact of AD on quality of life. Its applicability in research and clinical settings underscores its versatility. The study underscores the significance of clinical and demographic characteristics, along with the quality of life, for an accurate assessment of disease severity and effective treatment.</p>","PeriodicalId":8488,"journal":{"name":"Asia Pacific Allergy","volume":"15 2","pages":"49-56"},"PeriodicalIF":2.1000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289073/pdf/","citationCount":"0","resultStr":"{\"title\":\"Assessment of the quality of life in patients with atopic dermatitis using the Kazakh version of the questionnaire \\\"Dermatology Life Quality Index\\\".\",\"authors\":\"Gulya Sarybayeva, Ulzhan Beisebayeva, Leila Almenova, Askar Khabizhanov, Saniya Ospanova, Dinara Rysbekova, Zhanat Ispayeva, Shynar Tanabayeva, Timur Saliev, Ildar Fakhradiyev\",\"doi\":\"10.5415/apallergy.0000000000000183\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The effectiveness of the Dermatology Life Quality Index (DLQI), translated into Kazakh, for assessing the quality of life of patients with atopic dermatitis (AD) in Kazakhstan, has not yet been evaluated.</p><p><strong>Objective: </strong>The aim of the study is to assess the reliability and validity of the Kazakh language DLQI as a tool for assessing the quality of life of patients with AD.</p><p><strong>Methods: </strong>This multicenter study involved 883 adult patients of the Kazakh population diagnosed with AD. To assess the quality of life of AD patients, the DLQI questionnaire translated into Kazakh was used.</p><p><strong>Results: </strong>The reliability (Cronbach <i>α</i>) of the Kazakh version DLQI questionnaire was -0.924. The average DLQI score for the sample was 10.7 ± 8.2. Nearly 53.8% of patients had mild AD and 35.3% had moderate AD. According to the DLQI questionnaire, the average score increases with rising body mass index: patients who are overweight (11.9 ± 8.5) and those with obesity of the first degree (13.1 ± 9.0) have scores indicating a significant impact of the skin disease on their quality of life, whereas patients with normal weight (10.2 ± 8.0) or underweight (7.9 ± 7.4) experienced a more moderate effect, <i>P</i> = 0.001. Relapses 2 times a year (12.2 ± 8.5) and 3 or more times a year (12.6 ± 8.7) worsened the quality of life relatively more than relapses 1 time per year, <i>P</i> = 0.001. Smoking and alcohol consumption affected the deterioration in the quality of life of patients with AD (<i>P</i> ≤ 0.05). The quality of life of patients with AD in remission according to the DLQI scale was higher, <i>P</i> = 0.001.</p><p><strong>Conclusion: </strong>The results demonstrate that the Kazakh language version of the DLQI is a reliable and valid tool for measuring the impact of AD on quality of life. Its applicability in research and clinical settings underscores its versatility. The study underscores the significance of clinical and demographic characteristics, along with the quality of life, for an accurate assessment of disease severity and effective treatment.</p>\",\"PeriodicalId\":8488,\"journal\":{\"name\":\"Asia Pacific Allergy\",\"volume\":\"15 2\",\"pages\":\"49-56\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289073/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asia Pacific Allergy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5415/apallergy.0000000000000183\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/5 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asia Pacific Allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5415/apallergy.0000000000000183","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/5 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ALLERGY","Score":null,"Total":0}
Assessment of the quality of life in patients with atopic dermatitis using the Kazakh version of the questionnaire "Dermatology Life Quality Index".
Background: The effectiveness of the Dermatology Life Quality Index (DLQI), translated into Kazakh, for assessing the quality of life of patients with atopic dermatitis (AD) in Kazakhstan, has not yet been evaluated.
Objective: The aim of the study is to assess the reliability and validity of the Kazakh language DLQI as a tool for assessing the quality of life of patients with AD.
Methods: This multicenter study involved 883 adult patients of the Kazakh population diagnosed with AD. To assess the quality of life of AD patients, the DLQI questionnaire translated into Kazakh was used.
Results: The reliability (Cronbach α) of the Kazakh version DLQI questionnaire was -0.924. The average DLQI score for the sample was 10.7 ± 8.2. Nearly 53.8% of patients had mild AD and 35.3% had moderate AD. According to the DLQI questionnaire, the average score increases with rising body mass index: patients who are overweight (11.9 ± 8.5) and those with obesity of the first degree (13.1 ± 9.0) have scores indicating a significant impact of the skin disease on their quality of life, whereas patients with normal weight (10.2 ± 8.0) or underweight (7.9 ± 7.4) experienced a more moderate effect, P = 0.001. Relapses 2 times a year (12.2 ± 8.5) and 3 or more times a year (12.6 ± 8.7) worsened the quality of life relatively more than relapses 1 time per year, P = 0.001. Smoking and alcohol consumption affected the deterioration in the quality of life of patients with AD (P ≤ 0.05). The quality of life of patients with AD in remission according to the DLQI scale was higher, P = 0.001.
Conclusion: The results demonstrate that the Kazakh language version of the DLQI is a reliable and valid tool for measuring the impact of AD on quality of life. Its applicability in research and clinical settings underscores its versatility. The study underscores the significance of clinical and demographic characteristics, along with the quality of life, for an accurate assessment of disease severity and effective treatment.
期刊介绍：
Asia Pacific Allergy (AP Allergy) is the official journal of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). Although the primary aim of the journal is to promote communication between Asia Pacific scientists who are interested in allergy, asthma, and clinical immunology including immunodeficiency, the journal is intended to be available worldwide. To enable scientists and clinicians from emerging societies appreciate the scope and intent of the journal, early issues will contain more educational review material. For better communication and understanding, it will include rational concepts related to the diagnosis and management of asthma and other immunological conditions. Over time, the journal will increase the number of original research papers to become the foremost citation journal for allergy and clinical immunology information of the Asia Pacific in the future.
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