Rachel Duhan Wåhlberg, Victoria Franke Stenport, Ann Wennerberg, Lars Hjalmarsson
{"title":"早期种植体失败相关因素的多中心研究-第2部分：患者因素","authors":"Rachel Duhan Wåhlberg, Victoria Franke Stenport, Ann Wennerberg, Lars Hjalmarsson","doi":"10.1111/cid.70081","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Recent advancements in dental implant materials, designs, and surgery have increased their use, especially for challenging local conditions. As guidelines for individualized risk assessment are increasingly emphasized, implant treatment has become available to patients with diverse medical backgrounds. However, clinical research with large patient groups is needed to investigate the effects of patient-related factors associated with early implant failure.</p>\n </section>\n \n <section>\n \n <h3> Purpose</h3>\n \n <p>This paper investigates patient factors in two patient cohorts associated with early implant complications and failures.</p>\n </section>\n \n <section>\n \n <h3> Materials and Methods</h3>\n \n <p>The collected data were analyzed and presented in two studies. Both studies followed the same data collection methodology and compared cohorts treated in 2007 and 2017. The same patient-level dataset was analyzed, although the second study included additional analyses of diseases and allergies. Data were analyzed univariately (<i>p</i> < 0.20) to select variables for the multivariable logistic regression model (<i>p</i> < 0.05), with early implant failures and complications as dependent variables.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>In total, 1875 patients with 4670 implants were included. There were 74 (3.7%) dropouts, mainly due to lack of data. The 2007 cohort comprised 799 patients with 2473 implants, and the 2017 cohort comprised 1076 patients with 2287 implants. Differences were observed between the two cohorts for the number of implants per patient, exposed implant threads, and preoperative antibiotics. In the 2007 cohort, 23 (2.9%) patients had early implant failure. In the 2017 cohort, 40 (3.7%) had early implant failure (<i>p</i> > 0.30). Significantly more implants failed in the 2017 cohort (<i>n</i> = 56, 2.4%) than in the 2007 cohort (<i>n</i> = 26, 1.1%) (<i>p</i> < 0.001). Early complications were reported for 56 (7.0%) patients in 2007 and 145 (13.5%) patients in 2017 (<i>p</i> < 0.001). Three patient-related variables were associated with an increased risk of early failure—food allergy, exposed implant threads, and increased number of implants. Seven variables were related to an increased risk of complications: smoking, exposed threads, no preoperative antibiotics, number of implants, sinus perforations, food allergy, and metal allergy.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>This study identified three factors associated with early implant failure and seven associated with early complications.</p>\n </section>\n </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 4","pages":""},"PeriodicalIF":4.0000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70081","citationCount":"0","resultStr":"{\"title\":\"A Multicenter Study of Factors Related to Early Implant Failures—Part 2: Patient Factors\",\"authors\":\"Rachel Duhan Wåhlberg, Victoria Franke Stenport, Ann Wennerberg, Lars Hjalmarsson\",\"doi\":\"10.1111/cid.70081\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Recent advancements in dental implant materials, designs, and surgery have increased their use, especially for challenging local conditions. As guidelines for individualized risk assessment are increasingly emphasized, implant treatment has become available to patients with diverse medical backgrounds. However, clinical research with large patient groups is needed to investigate the effects of patient-related factors associated with early implant failure.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Purpose</h3>\\n \\n <p>This paper investigates patient factors in two patient cohorts associated with early implant complications and failures.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials and Methods</h3>\\n \\n <p>The collected data were analyzed and presented in two studies. Both studies followed the same data collection methodology and compared cohorts treated in 2007 and 2017. The same patient-level dataset was analyzed, although the second study included additional analyses of diseases and allergies. Data were analyzed univariately (<i>p</i> < 0.20) to select variables for the multivariable logistic regression model (<i>p</i> < 0.05), with early implant failures and complications as dependent variables.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>In total, 1875 patients with 4670 implants were included. There were 74 (3.7%) dropouts, mainly due to lack of data. The 2007 cohort comprised 799 patients with 2473 implants, and the 2017 cohort comprised 1076 patients with 2287 implants. Differences were observed between the two cohorts for the number of implants per patient, exposed implant threads, and preoperative antibiotics. In the 2007 cohort, 23 (2.9%) patients had early implant failure. In the 2017 cohort, 40 (3.7%) had early implant failure (<i>p</i> > 0.30). Significantly more implants failed in the 2017 cohort (<i>n</i> = 56, 2.4%) than in the 2007 cohort (<i>n</i> = 26, 1.1%) (<i>p</i> < 0.001). Early complications were reported for 56 (7.0%) patients in 2007 and 145 (13.5%) patients in 2017 (<i>p</i> < 0.001). Three patient-related variables were associated with an increased risk of early failure—food allergy, exposed implant threads, and increased number of implants. 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A Multicenter Study of Factors Related to Early Implant Failures—Part 2: Patient Factors
Background
Recent advancements in dental implant materials, designs, and surgery have increased their use, especially for challenging local conditions. As guidelines for individualized risk assessment are increasingly emphasized, implant treatment has become available to patients with diverse medical backgrounds. However, clinical research with large patient groups is needed to investigate the effects of patient-related factors associated with early implant failure.
Purpose
This paper investigates patient factors in two patient cohorts associated with early implant complications and failures.
Materials and Methods
The collected data were analyzed and presented in two studies. Both studies followed the same data collection methodology and compared cohorts treated in 2007 and 2017. The same patient-level dataset was analyzed, although the second study included additional analyses of diseases and allergies. Data were analyzed univariately (p < 0.20) to select variables for the multivariable logistic regression model (p < 0.05), with early implant failures and complications as dependent variables.
Results
In total, 1875 patients with 4670 implants were included. There were 74 (3.7%) dropouts, mainly due to lack of data. The 2007 cohort comprised 799 patients with 2473 implants, and the 2017 cohort comprised 1076 patients with 2287 implants. Differences were observed between the two cohorts for the number of implants per patient, exposed implant threads, and preoperative antibiotics. In the 2007 cohort, 23 (2.9%) patients had early implant failure. In the 2017 cohort, 40 (3.7%) had early implant failure (p > 0.30). Significantly more implants failed in the 2017 cohort (n = 56, 2.4%) than in the 2007 cohort (n = 26, 1.1%) (p < 0.001). Early complications were reported for 56 (7.0%) patients in 2007 and 145 (13.5%) patients in 2017 (p < 0.001). Three patient-related variables were associated with an increased risk of early failure—food allergy, exposed implant threads, and increased number of implants. Seven variables were related to an increased risk of complications: smoking, exposed threads, no preoperative antibiotics, number of implants, sinus perforations, food allergy, and metal allergy.
Conclusions
This study identified three factors associated with early implant failure and seven associated with early complications.
期刊介绍：
The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal.
The range of topics covered by the journals will include but be not limited to:
New scientific developments relating to bone
Implant surfaces and their relationship to the surrounding tissues
Computer aided implant designs
Computer aided prosthetic designs
Immediate implant loading
Immediate implant placement
Materials relating to bone induction and conduction
New surgical methods relating to implant placement
New materials and methods relating to implant restorations
Methods for determining implant stability
A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.
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