F.D. Favier , G.C.M. Grinwis , A.H. Hulsman , M. den Toom , F.G. van Steenbeek , G. Santarelli
{"title":"三岁可卡犬疑似心律失常性心肌病相关的三度房室传导阻滞","authors":"F.D. Favier , G.C.M. Grinwis , A.H. Hulsman , M. den Toom , F.G. van Steenbeek , G. Santarelli","doi":"10.1016/j.jvc.2025.06.008","DOIUrl":null,"url":null,"abstract":"<div><div>A three-year-old spayed female English Cocker spaniel was presented with diarrhea, abdominal distension, and exercise intolerance. On physical examination, bradycardia, abdominal distension with positive undulation, and a soft systolic right-sided heart murmur were detected. Electrocardiography showed a third-degree atrioventricular block with monomorphic idioventricular rhythm and premature ventricular ectopic beats. On echocardiography, an extremely thin right ventricular wall, severe right ventricular and atrial dilation, and severely depressed right ventricular systolic function were observed, and ascites was confirmed. Despite pacemaker implantation and standard treatment for congestive heart failure, the dog's condition deteriorated quickly, leading to euthanasia. Pathological examination showed a thin right ventricular free wall with fibrosis and largely absent cardiomyocytes, along with myocardial infiltration of adipocytes and lymphocytes. An arrhythmogenic cardiomyopathy complicated with a third-degree atrioventricular block was considered the most likely diagnosis.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"61 ","pages":"Pages 51-55"},"PeriodicalIF":1.3000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Third-degree atrioventricular block associated with suspected arrhythmogenic cardiomyopathy in a three-year-old Cocker Spaniel\",\"authors\":\"F.D. Favier , G.C.M. Grinwis , A.H. Hulsman , M. den Toom , F.G. van Steenbeek , G. Santarelli\",\"doi\":\"10.1016/j.jvc.2025.06.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A three-year-old spayed female English Cocker spaniel was presented with diarrhea, abdominal distension, and exercise intolerance. On physical examination, bradycardia, abdominal distension with positive undulation, and a soft systolic right-sided heart murmur were detected. Electrocardiography showed a third-degree atrioventricular block with monomorphic idioventricular rhythm and premature ventricular ectopic beats. On echocardiography, an extremely thin right ventricular wall, severe right ventricular and atrial dilation, and severely depressed right ventricular systolic function were observed, and ascites was confirmed. Despite pacemaker implantation and standard treatment for congestive heart failure, the dog's condition deteriorated quickly, leading to euthanasia. Pathological examination showed a thin right ventricular free wall with fibrosis and largely absent cardiomyocytes, along with myocardial infiltration of adipocytes and lymphocytes. An arrhythmogenic cardiomyopathy complicated with a third-degree atrioventricular block was considered the most likely diagnosis.</div></div>\",\"PeriodicalId\":48788,\"journal\":{\"name\":\"Journal of Veterinary Cardiology\",\"volume\":\"61 \",\"pages\":\"Pages 51-55\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Veterinary Cardiology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1760273425000657\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Cardiology","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1760273425000657","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Third-degree atrioventricular block associated with suspected arrhythmogenic cardiomyopathy in a three-year-old Cocker Spaniel
A three-year-old spayed female English Cocker spaniel was presented with diarrhea, abdominal distension, and exercise intolerance. On physical examination, bradycardia, abdominal distension with positive undulation, and a soft systolic right-sided heart murmur were detected. Electrocardiography showed a third-degree atrioventricular block with monomorphic idioventricular rhythm and premature ventricular ectopic beats. On echocardiography, an extremely thin right ventricular wall, severe right ventricular and atrial dilation, and severely depressed right ventricular systolic function were observed, and ascites was confirmed. Despite pacemaker implantation and standard treatment for congestive heart failure, the dog's condition deteriorated quickly, leading to euthanasia. Pathological examination showed a thin right ventricular free wall with fibrosis and largely absent cardiomyocytes, along with myocardial infiltration of adipocytes and lymphocytes. An arrhythmogenic cardiomyopathy complicated with a third-degree atrioventricular block was considered the most likely diagnosis.
期刊介绍:
The mission of the Journal of Veterinary Cardiology is to publish peer-reviewed reports of the highest quality that promote greater understanding of cardiovascular disease, and enhance the health and well being of animals and humans. The Journal of Veterinary Cardiology publishes original contributions involving research and clinical practice that include prospective and retrospective studies, clinical trials, epidemiology, observational studies, and advances in applied and basic research.
The Journal invites submission of original manuscripts. Specific content areas of interest include heart failure, arrhythmias, congenital heart disease, cardiovascular medicine, surgery, hypertension, health outcomes research, diagnostic imaging, interventional techniques, genetics, molecular cardiology, and cardiovascular pathology, pharmacology, and toxicology.