甲型肝炎疫苗接种在英格兰：一个系统的挑战

IF 25.2 1区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Lancet Public Health Pub Date : 2025-07-28 DOI:10.1016/s2468-2667(25)00149-5

Sema Mandal, David Leeman, Mary E Ramsay

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引用次数: 0

摘要

在英格兰诊断出的大多数甲型肝炎散发病例都与到流行国家旅行有关。偶尔暴发是由最初输入或受污染食物后的人际传播引起的。3,4由于甲型肝炎在英国的发病率很低，甲型肝炎免疫接种只推荐给高危人群（包括前往流行国家的旅行者、注射吸毒者和男男性行为者）和并发症风险增加的人群，如慢性肝病患者5，感染可能导致急性暴发性肝炎和潜在死亡

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Hepatitis A targeted vaccination in England: a system challenge

Most sporadic cases of hepatitis A diagnosed in England are associated with travel to endemic countries. Occasional outbreaks result from person-to-person transmission following initial importations² or contaminated food.3, 4 Since hepatitis A incidence in the UK is low, hepatitis A immunisation is only recommended for people at high risk of exposure (including travellers to endemic countries, people who inject drugs, and men who have sex with men) and for those at increased risk of complications, such as people with chronic liver disease,⁵ in whom infection might lead to acute fulminant hepatitis and potentially death.⁶

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来源期刊

Lancet Public Health Medicine-Public Health, Environmental and Occupational Health

CiteScore

55.60

自引率

0.80%

发文量

305

审稿时长

8 weeks

期刊介绍： The Lancet Public Health is committed to tackling the most pressing issues across all aspects of public health. We have a strong commitment to using science to improve health equity and social justice. In line with the values and vision of The Lancet, we take a broad and inclusive approach to public health and are interested in interdisciplinary research. We publish a range of content types that can advance public health policies and outcomes. These include Articles, Review, Comment, and Correspondence. Learn more about the types of papers we publish.