异质结构COF/TiO 2 /MWCNT-COOH复合传感器用于多巴胺和尿酸的同时和单独电化学检测

IF 6.3 2区 材料科学 Q2 CHEMISTRY, PHYSICAL
Ya-Xin Li, Dong-Mei Ma, Ming-Xia Wang, Cheng Wang, Fu-Fa Wu, Rong-Da Zhao, Jun Xiang, Xing-Ming Zhao, Tian-Lin Wang
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引用次数: 0

摘要

在这项研究中,我们采用了一种创新的策略,通过整合双功能共价有机框架(COF)、纳米二氧化钛(TiO2)和羧化多壁碳纳米管(MWCNT-COOH)来构建异质结构复合材料。通过强化学键作用,TiO2和MWCNT-COOH成功地固定在COF上,形成了COF/TiO2/MWCNT-COOH异质结复合材料。该复合物随后应用于多巴胺(DA)和尿酸(UA)的高灵敏度和选择性检测。通过亚胺键形成合成的双功能COF具有较大的比表面积。在TiO2的催化作用下,复合材料暴露了额外的活性位点,从而促进了MWCNT-COOH运输的生物分子的高效双电子转移过程。COF、TiO2和MWCNT-COOH之间的协同作用显著提高了生物传感器的分析性能,特别是在DA和UA的吸附和富集方面。实验结果表明,该电化学生物传感器的DA检测下限为0.0236 μM,线性检测范围为0.3 μM ~ 500 μM。对于UA, LOD为0.0829 μM,线性范围为0.1 μM ~ 800 μM。此外,该传感器具有良好的选择性、重复性、抗干扰能力强、长期稳定性,在电化学生物传感领域具有重要的实际应用潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Heterostructured COF/TiO₂/MWCNT-COOH composite sensor for simultaneous and individual electrochemical detection of dopamine and uric acid
In this study, we employed an innovative strategy to construct a heterostructured composite material by integrating a bifunctional covalent organic framework (COF), nano-titanium dioxide (TiO2), and carboxylated multi-walled carbon nanotubes (MWCNT-COOH). Through strong chemical bonding interactions, TiO2 and MWCNT-COOH were successfully anchored onto the COF, resulting in the formation of a COF/TiO2/MWCNT-COOH heterojunction composite. This composite was subsequently applied for the highly sensitive and selective detection of dopamine (DA) and uric acid (UA). The bifunctional COF, synthesized via imine bond formation, possesses a large specific surface area. Under the catalytic influence of TiO2, the composite material exposes additional active sites, thereby facilitating an efficient two-electron transfer process for the biomolecules transported by MWCNT-COOH. The synergistic interactions among the COF, TiO2, and MWCNT-COOH significantly enhance the biosensor's analytical performance, particularly in terms of adsorption and enrichment of DA and UA. Experimental results reveal that the fabricated electrochemical biosensor achieves an impressively low limit of detection (LOD) of 0.0236 μM for DA, with a linear detection range of 0.3 μM to 500 μM. For UA, the LOD is 0.0829 μM, with a linear range from 0.1 μM to 800 μM. Moreover, the biosensor demonstrates excellent selectivity, reproducibility, strong anti-interference capabilities, and long-term stability, highlighting its significant potential for practical applications in electrochemical biosensing.
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来源期刊
Journal of Alloys and Compounds
Journal of Alloys and Compounds 工程技术-材料科学:综合
CiteScore
11.10
自引率
14.50%
发文量
5146
审稿时长
67 days
期刊介绍: The Journal of Alloys and Compounds is intended to serve as an international medium for the publication of work on solid materials comprising compounds as well as alloys. Its great strength lies in the diversity of discipline which it encompasses, drawing together results from materials science, solid-state chemistry and physics.
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