脑瘫患儿呼吸系统住院率能降低吗？可行性随机对照试验（respa - act）。

IF 3.5 2区医学 Q1 PEDIATRICS

Journal of Pediatrics Pub Date : 2025-07-24 DOI:10.1016/j.jpeds.2025.114755

Rachael M. Marpole FRACP , A Marie Blackmore PhD , Andrew C. Wilson FRACP , Monica S. Cooper PhD , Julie Depiazzi Master Phil , Katherine Langdon FRACP , Lisa Moshovis BS , Asha C. Bowen PhD , Noula Gibson PhD

{"title":"脑瘫患儿呼吸系统住院率能降低吗？可行性随机对照试验（respa - act）。","authors":"Rachael M. Marpole FRACP , A Marie Blackmore PhD , Andrew C. Wilson FRACP , Monica S. Cooper PhD , Julie Depiazzi Master Phil , Katherine Langdon FRACP , Lisa Moshovis BS , Asha C. Bowen PhD , Noula Gibson PhD","doi":"10.1016/j.jpeds.2025.114755","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the feasibility of implementing recommendations of the consensus statement for the Prevention and Management of Respiratory Disease in children with severe cerebral palsy (CP) via RESPiratory hospital Admissions in children with cerebral palsy: a feasibility randomized Controlled Trial (RESP-ACT).</div></div><div><h3>Study design</h3><div>Twenty-two children with CP aged 0-12 years at risk of respiratory disease and receiving care through Perth Children's Hospital in Western Australia were randomized into parallel groups. The control group (n = 10) continued with their usual teams, while the intervention group (n = 12) received a comprehensive assessment followed by individualized investigations and appointments as needed. The primary outcomes include implementation, acceptability, practicality, and measuring efficacy. During the following year, with the help of a blind assessor, caregivers reported their children's health service use on a fortnightly basis. Caregivers and treating clinicians were interviewed at the end of the trial.</div></div><div><h3>Results</h3><div>Complete data were obtained from 73% of participants at 1 year. They completed 89% of the fortnightly surveys. Hospital service data were assessed for all. The 9 intervention participants interviewed at the end of the trial were satisfied or very satisfied with the service, and all caregivers and clinicians agreed or strongly agreed that such a service should be established. Their practical concerns included managing time, preference for home-based interventions and adequate staffing.</div></div><div><h3>Conclusions</h3><div>The service is feasible to implement but requires close monitoring. This trial provides data on which to base a larger randomized control trial.</div></div><div><h3>Trial registration</h3><div>Australian New Zealand Clinical Trials Registry-Registration number 12620000114943.</div></div>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"287 ","pages":"Article 114755"},"PeriodicalIF":3.5000,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Can Respiratory Hospital Admissions in Children with Cerebral Palsy Be Reduced? A Feasibility Randomized Controlled Trial (RESP-ACT)\",\"authors\":\"Rachael M. Marpole FRACP , A Marie Blackmore PhD , Andrew C. Wilson FRACP , Monica S. Cooper PhD , Julie Depiazzi Master Phil , Katherine Langdon FRACP , Lisa Moshovis BS , Asha C. Bowen PhD , Noula Gibson PhD\",\"doi\":\"10.1016/j.jpeds.2025.114755\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To investigate the feasibility of implementing recommendations of the consensus statement for the Prevention and Management of Respiratory Disease in children with severe cerebral palsy (CP) via RESPiratory hospital Admissions in children with cerebral palsy: a feasibility randomized Controlled Trial (RESP-ACT).</div></div><div><h3>Study design</h3><div>Twenty-two children with CP aged 0-12 years at risk of respiratory disease and receiving care through Perth Children's Hospital in Western Australia were randomized into parallel groups. The control group (n = 10) continued with their usual teams, while the intervention group (n = 12) received a comprehensive assessment followed by individualized investigations and appointments as needed. The primary outcomes include implementation, acceptability, practicality, and measuring efficacy. During the following year, with the help of a blind assessor, caregivers reported their children's health service use on a fortnightly basis. Caregivers and treating clinicians were interviewed at the end of the trial.</div></div><div><h3>Results</h3><div>Complete data were obtained from 73% of participants at 1 year. They completed 89% of the fortnightly surveys. Hospital service data were assessed for all. The 9 intervention participants interviewed at the end of the trial were satisfied or very satisfied with the service, and all caregivers and clinicians agreed or strongly agreed that such a service should be established. Their practical concerns included managing time, preference for home-based interventions and adequate staffing.</div></div><div><h3>Conclusions</h3><div>The service is feasible to implement but requires close monitoring. This trial provides data on which to base a larger randomized control trial.</div></div><div><h3>Trial registration</h3><div>Australian New Zealand Clinical Trials Registry-Registration number 12620000114943.</div></div>\",\"PeriodicalId\":54774,\"journal\":{\"name\":\"Journal of Pediatrics\",\"volume\":\"287 \",\"pages\":\"Article 114755\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pediatrics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0022347625002963\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pediatrics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022347625002963","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}

引用次数: 0

摘要

目的：探讨通过脑瘫患儿呼吸系统住院预防和管理重症脑瘫患儿呼吸系统疾病共识声明建议实施的可行性：可行性随机对照试验（respa - act）。研究设计：22名0-12岁有呼吸道疾病风险并在西澳大利亚珀斯儿童医院接受治疗的CP儿童随机分为平行组。对照组（n=10）继续他们的常规小组，而干预组（n=12）接受综合评估，然后根据需要进行个性化调查和预约。主要结果包括实施、可接受性、实用性和测量有效性。在接下来的一年里，在一名盲人评估员的帮助下，照料者每两周报告一次其子女使用保健服务的情况。在试验结束时，对护理人员和治疗临床医生进行了采访。结果：73%的参与者在1年内获得了完整的数据。他们完成了89%的两周一次的调查。对所有患者的医院服务数据进行了评估。在试验结束时接受采访的9名干预参与者对该服务满意或非常满意，所有护理人员和临床医生都同意或强烈同意应该建立这样的服务。他们实际关心的问题包括管理时间、偏爱以家庭为基础的干预措施和适当的人员配备。结论：该服务实施可行，但需密切监测。该试验为更大规模的随机对照试验提供了数据基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Can Respiratory Hospital Admissions in Children with Cerebral Palsy Be Reduced? A Feasibility Randomized Controlled Trial (RESP-ACT)

Objective

To investigate the feasibility of implementing recommendations of the consensus statement for the Prevention and Management of Respiratory Disease in children with severe cerebral palsy (CP) via RESPiratory hospital Admissions in children with cerebral palsy: a feasibility randomized Controlled Trial (RESP-ACT).

Study design

Twenty-two children with CP aged 0-12 years at risk of respiratory disease and receiving care through Perth Children's Hospital in Western Australia were randomized into parallel groups. The control group (n = 10) continued with their usual teams, while the intervention group (n = 12) received a comprehensive assessment followed by individualized investigations and appointments as needed. The primary outcomes include implementation, acceptability, practicality, and measuring efficacy. During the following year, with the help of a blind assessor, caregivers reported their children's health service use on a fortnightly basis. Caregivers and treating clinicians were interviewed at the end of the trial.

Results

Complete data were obtained from 73% of participants at 1 year. They completed 89% of the fortnightly surveys. Hospital service data were assessed for all. The 9 intervention participants interviewed at the end of the trial were satisfied or very satisfied with the service, and all caregivers and clinicians agreed or strongly agreed that such a service should be established. Their practical concerns included managing time, preference for home-based interventions and adequate staffing.

Conclusions

The service is feasible to implement but requires close monitoring. This trial provides data on which to base a larger randomized control trial.

Trial registration

Australian New Zealand Clinical Trials Registry-Registration number 12620000114943.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Pediatrics 医学-小儿科

CiteScore

6.00

自引率

2.00%

发文量

696

审稿时长

31 days

期刊介绍： The Journal of Pediatrics is an international peer-reviewed journal that advances pediatric research and serves as a practical guide for pediatricians who manage health and diagnose and treat disorders in infants, children, and adolescents. The Journal publishes original work based on standards of excellence and expert review. The Journal seeks to publish high quality original articles that are immediately applicable to practice (basic science, translational research, evidence-based medicine), brief clinical and laboratory case reports, medical progress, expert commentary, grand rounds, insightful editorials, “classic” physical examinations, and novel insights into clinical and academic pediatric medicine related to every aspect of child health. Published monthly since 1932, The Journal of Pediatrics continues to promote the latest developments in pediatric medicine, child health, policy, and advocacy. Topics covered in The Journal of Pediatrics include, but are not limited to: General Pediatrics Pediatric Subspecialties Adolescent Medicine Allergy and Immunology Cardiology Critical Care Medicine Developmental-Behavioral Medicine Endocrinology Gastroenterology Hematology-Oncology Infectious Diseases Neonatal-Perinatal Medicine Nephrology Neurology Emergency Medicine Pulmonology Rheumatology Genetics Ethics Health Service Research Pediatric Hospitalist Medicine.