2019冠状病毒病大流行和大流行后经济危机对斯里兰卡农村蛇咬伤模式的影响

IF 2.4 4区医学 Q2 PHARMACOLOGY & PHARMACY

Toxicon Pub Date : 2025-07-24 DOI:10.1016/j.toxicon.2025.108502

Subodha Waiddyanatha , Anjana Silva , Asela Wijayasekara , Supun Wedasingha , Sisira Siribaddana , Geoffrey K. Isbister

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引用次数: 0

摘要

目的：我们旨在比较斯里兰卡一个蛇咬伤发生率高的地区在2019冠状病毒病期间、之前和之后的蛇咬伤模式和蛇咬伤受害者的院前做法。方法：从2018年3月至2023年10月的阿努拉德拉普勒蛇咬伤队列中提取数据。该队列招募了阿努拉德拉普勒教学医院收治的所有蛇咬伤患者（16岁以上）。本研究分析了COVID前（2018年3月至2019年10月），COVID（2020年3月至2021年10月）和COVID后（2022年3月至2023年10月）期间的数据。结果：在COVID前，COVID和COVID后组中分别有1141,1312和1375例患者。与前（234/658,36%）相比，经认证的Hypnale在COVID期间（454/784,58%）和COVID后（501/849,59%）的叮咬量有所增加，而rusboia russelii在COVID期间（210/784,27%）和COVID后（205/849,24%）的叮咬量与前（259/658,39%）相比有所减少。与新冠肺炎前（378/1141,33%）和新冠肺炎后（416/1312,32%）相比，新冠肺炎后家庭花园咬伤的比例（56 /1375,41%）有所增加。与COVID前（18%）和COVID前（16%）组相比，COVID后故意延迟住院的患者比例（26%）更高。入院前寻求原生治疗的比例在COVID后（15%）高于COVID前（6%）和COVID期间（7%），在COVID后使用止血带作为急救（37%）高于COVID前（22%）和COVID（22%）。在COVID-19大流行期间，患者不遵医嘱离开医院的比例从COVID-19前的3%上升至4%。这一趋势在大流行之后继续增加。结论：在2019冠状病毒病大流行期间和之后，hypnale H.病例增加，russelii D.咬伤减少，与蛇咬伤从农田向家庭花园转移的趋势一致。在COVID-19大流行期间和之后，更多的患者延误了医院治疗，使用了有害的急救措施，或不遵医嘱离开。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The impact of the COVID-19 pandemic and post-pandemic economic crisis on snakebite patterns in rural Sri Lanka

查看原文本刊更多论文

The impact of the COVID-19 pandemic and post-pandemic economic crisis on snakebite patterns in rural Sri Lanka

Aim

We aimed to compare the pattern of snakebites and the pre-hospital practices of snakebite victims during, before, and after the COVID-19 period in a region of Sri Lanka with a high snakebite incidence.

Methods

Data were extracted from the Anuradhapura snakebite cohort from March 2018 to October 2023. The cohort recruits all snakebite patients (>16 years) admitted to the Teaching Hospital, Anuradhapura. For this study, data from pre-COVID (March 2018–October 2019), COVID (March 2020–October 2021), and post-COVID (March 2022–October 2023) periods were analysed.

Results

There were 1141, 1312, and 1375 patients in the Pre-COVID, COVID and Post-COVID groups. Authenticated Hypnale hypnale bites increased during COVID (454/784, 58 %) and post-COVID (501/849,59 %) compared to pre-COVID (234/658, 36 %), while Daboia russelii bites decreased during COVID (210/784, 27 %) and post-COVID (205/849, 24 %) compared to pre-COVID (259/658, 39 %). The proportion of home garden bites increased during post-COVID (560/1375, 41 %) compared to pre-COVID (378/1141, 33 %) and COVID (416/1312, 32 %). The percentage of patients who intentionally delayed hospital admission was greater in post-COVID (26 %) compared to groups pre-COVID (18 %) and COVID (16 %). The percentage who sought native treatment before hospital admission was greater post-COVID (15 %) compared to pre-COVID (6 %) and during COVID (7 %), as was the application of tourniquets as first aid post-COVID (37 %) compared to pre-COVID (22 %) and COVID (22 %). During the COVID-19 pandemic, the rate of patients leaving the hospital against medical advice rose to 4 %, up from 3 % in the pre-COVID period. This trend continued to increase after the pandemic.

Conclusion

During and after the COVID-19 pandemic, H. hypnale cases increased and D. russelii bites decreased, coinciding with shift of snakebites from farmlands to home gardens. More patients delayed hospital treatment, used harmful first aid, or left against medical advice during and after the COVID-19 pandemic.

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来源期刊

Toxicon 医学-毒理学

CiteScore

4.80

自引率

10.70%

发文量

358

审稿时长

68 days

期刊介绍： Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee. Toxicon''s "aims and scope" are to publish: -articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms -papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins -molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins -clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained. -material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems. -articles on the translational application of toxins, for example as drugs and insecticides -epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged. -articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon. -review articles on problems related to toxinology. To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.