Wei Deng, Guiyi Zhao, Yudong Xiao, Kaixin Guo, Sien Zhang, Guiqing Liao, Le Yang, Yujie Liang
{"title":"青少年和青年口腔癌患者的语言和吞咽障碍","authors":"Wei Deng, Guiyi Zhao, Yudong Xiao, Kaixin Guo, Sien Zhang, Guiqing Liao, Le Yang, Yujie Liang","doi":"10.1111/odi.70041","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the speech and swallowing function and recovery status in adolescent and young adult (AYAs) patients with oral cavity cancer (OCC).</p><p><strong>Methods: </strong>A cohort study was conducted in AYAs patients with OCC from August 2019 to April 2021. The swallowing and speech functions were evaluated by M.D. Anderson dysphagia inventory (MDADI), 10-item eating assessment tool (EAT-10) and speech handicap index (SHI) at pretreatment and postoperative stages. Multiple linear regression and linear mixed models were employed.</p><p><strong>Results: </strong>A total of 661 patients were enrolled, including 143 AYAs and 518 individuals aged ≥ 40. The preoperative total scores of MDADI, EAT-10, and SHI were worse in AYAs patients. AYAs patients with advanced T stage (T<sub>3</sub>-T<sub>4</sub>) before surgery exhibited worse scores for MDADI, EAT-10, and SHI. All patients presented the poorest outcomes within the initial 3 months postoperatively. However, a more rapid recovery trend of swallowing and speech function was demonstrated in the AYAs. Adjuvant radiotherapy/chemotherapy, advanced T stage (T<sub>3</sub>-T<sub>4</sub>), tracheostomy, or flap reconstruction were key risk factors of impairing speech and swallowing functions in AYAs patients.</p><p><strong>Conclusions: </strong>AYAs experience worse speech and swallowing function in the pretreatment stage and generally exhibit a higher potential for recovery.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Speech and Swallowing Disorders in Adolescent and Young Adults With Oral Cavity Cancer.\",\"authors\":\"Wei Deng, Guiyi Zhao, Yudong Xiao, Kaixin Guo, Sien Zhang, Guiqing Liao, Le Yang, Yujie Liang\",\"doi\":\"10.1111/odi.70041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the speech and swallowing function and recovery status in adolescent and young adult (AYAs) patients with oral cavity cancer (OCC).</p><p><strong>Methods: </strong>A cohort study was conducted in AYAs patients with OCC from August 2019 to April 2021. The swallowing and speech functions were evaluated by M.D. Anderson dysphagia inventory (MDADI), 10-item eating assessment tool (EAT-10) and speech handicap index (SHI) at pretreatment and postoperative stages. Multiple linear regression and linear mixed models were employed.</p><p><strong>Results: </strong>A total of 661 patients were enrolled, including 143 AYAs and 518 individuals aged ≥ 40. The preoperative total scores of MDADI, EAT-10, and SHI were worse in AYAs patients. AYAs patients with advanced T stage (T<sub>3</sub>-T<sub>4</sub>) before surgery exhibited worse scores for MDADI, EAT-10, and SHI. All patients presented the poorest outcomes within the initial 3 months postoperatively. However, a more rapid recovery trend of swallowing and speech function was demonstrated in the AYAs. Adjuvant radiotherapy/chemotherapy, advanced T stage (T<sub>3</sub>-T<sub>4</sub>), tracheostomy, or flap reconstruction were key risk factors of impairing speech and swallowing functions in AYAs patients.</p><p><strong>Conclusions: </strong>AYAs experience worse speech and swallowing function in the pretreatment stage and generally exhibit a higher potential for recovery.</p>\",\"PeriodicalId\":19615,\"journal\":{\"name\":\"Oral diseases\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/odi.70041\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/odi.70041","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Speech and Swallowing Disorders in Adolescent and Young Adults With Oral Cavity Cancer.
Objective: To evaluate the speech and swallowing function and recovery status in adolescent and young adult (AYAs) patients with oral cavity cancer (OCC).
Methods: A cohort study was conducted in AYAs patients with OCC from August 2019 to April 2021. The swallowing and speech functions were evaluated by M.D. Anderson dysphagia inventory (MDADI), 10-item eating assessment tool (EAT-10) and speech handicap index (SHI) at pretreatment and postoperative stages. Multiple linear regression and linear mixed models were employed.
Results: A total of 661 patients were enrolled, including 143 AYAs and 518 individuals aged ≥ 40. The preoperative total scores of MDADI, EAT-10, and SHI were worse in AYAs patients. AYAs patients with advanced T stage (T3-T4) before surgery exhibited worse scores for MDADI, EAT-10, and SHI. All patients presented the poorest outcomes within the initial 3 months postoperatively. However, a more rapid recovery trend of swallowing and speech function was demonstrated in the AYAs. Adjuvant radiotherapy/chemotherapy, advanced T stage (T3-T4), tracheostomy, or flap reconstruction were key risk factors of impairing speech and swallowing functions in AYAs patients.
Conclusions: AYAs experience worse speech and swallowing function in the pretreatment stage and generally exhibit a higher potential for recovery.
期刊介绍：
Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.
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