sfrp基因在假海棠再生过程中的表达模式

IF 2.4 4区生物学 Q2 DEVELOPMENTAL BIOLOGY

genesis Pub Date : 2025-07-29 DOI:10.1002/dvg.70023

Konstantin Sadriev

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引用次数: 0

摘要

分泌卷曲相关蛋白（SFRPs）是一个小的，古老的细胞外信号通路激动剂和拮抗剂家族。在这项研究中，我们使用全贴装原位杂交技术检测了它们在全息图鱼（holothurian Eupentacta fraudatmatrix）再生过程中的表达模式。我们的研究结果表明，这两个基因都参与了水-血管系统的形成和体腔上皮的稳态。

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Expression Patterns of sfrp Genes During Regeneration in the Holothurian Eupentacta fraudatrix

Secreted Frizzled-related proteins (SFRPs) are a small, ancient family of extracellular signaling pathway agonists and antagonists. In this study, we examined their expression patterns during regeneration in the holothurian Eupentacta fraudatrix using whole-mount in situ hybridization. Our results suggest that both genes are involved in proper water-vascular system formation and coelomic epithelium homeostasis in holothurians.

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来源期刊

genesis 生物-发育生物学

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： As of January 2000, Developmental Genetics was renamed and relaunched as genesis: The Journal of Genetics and Development, with a new scope and Editorial Board. The journal focuses on work that addresses the genetics of development and the fundamental mechanisms of embryological processes in animals and plants. With increased awareness of the interplay between genetics and evolutionary change, particularly during developmental processes, we encourage submission of manuscripts from all ecological niches. The expanded numbers of genomes for which sequencing is being completed will facilitate genetic and genomic examination of developmental issues, even if the model system does not fit the “classical genetic” mold. Therefore, we encourage submission of manuscripts from all species. Other areas of particular interest include: 1) the roles of epigenetics, microRNAs and environment on developmental processes; 2) genome-wide studies; 3) novel imaging techniques for the study of gene expression and cellular function; 4) comparative genetics and genomics and 5) animal models of human genetic and developmental disorders. genesis presents reviews, full research articles, short research letters, and state-of-the-art technology reports that promote an understanding of the function of genes and the roles they play in complex developmental processes.