评估高危委员会对成人颈椎畸形矫正手术的影响:对结果、并发症和接受术前多学科评估的手术频率的回顾性回顾

IF 3.1 2区 医学 Q2 CLINICAL NEUROLOGY
Kristen E Jones, Anthony Yung, Alyssa M Bartlett, Oluwatobi O Onafowokan, Peter S Tretiakov, Max R Fisher, Ethan Cottrill, Tyler K Williamson, Peter G Passias
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引用次数: 0

摘要

目的:目的是评估成人颈椎畸形(ACD)患者术前接受多学科检查的高危手术的频率、结果和影响。方法:根据是否接受高危回顾(HRR)对ACD患者进行分层。高危患者被定义为满足以下标准≥1项:颈椎前后路畸形融合≥3个级别;计划三柱截骨、脊柱切除和/或前柱改良;伴有严重基线神经功能缺损的畸形矫正;严重基线脊髓病(修正日本骨科协会评分< 11);重度骨质疏松,融合≥4级。统计学特征、影像学结果和并发症发生率的差异通过手段比较进行评估。调整基线年龄和改良ACD脆弱指数后,采用随访单变量单因素方差分析(ANCOVA)评估术后结果。Logistic回归评估委员会审查对并发症或再手术预测的影响。结果:149例ACD患者(平均±SD年龄57.5±10.9岁,58.2%为女性,体重指数28.5±7.8 kg/m2), 51.0% (n = 76)接受了委员会审查。基线时,队列在年龄、性别和BMI方面具有可比性,尽管根据修改的ACD衰弱指数,接受HRR (HRR+)的患者更脆弱(p < 0.001)。HRR+患者有心肌梗死史的可能性也显著增加(p = 0.045)。影像学上,HRR+患者在T1斜度减颈椎前凸(p = 0.031)和C2-7矢状垂直轴(p < 0.001)方面比未接受高危复查(HRR-)的患者更有可能出现更严重的畸形。围手术期,HRR-患者的平均手术时间明显更长(p < 0.001),更有可能接受任何截骨术(p = 0.020)或3柱截骨术(p = 0.045),尽管两组之间的总估计失血量、住院时间、外科重症监护病房入院和出院处置具有可比性(均p < 0.05)。两组间并发症发生率和死亡率也具有可比性(p < 0.05)。HRR+患者的再手术率较低(p = 0.037)。然而,调整后的回归分析显示,HRR既不能独立预测术中主要并发症,也不能预测再手术(p < 0.05)。结论:随着时间的推移,高风险委员会的实施与高风险程序的频率降低有关。但是,在设立这些委员会之后,发生并发症的危险并不一定会减少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing the impact of high-risk committees in adult cervical deformity corrective surgery: a retrospective review of outcomes, complications, and frequency of procedures receiving preoperative multidisciplinary evaluation.

Objective: The objective was to assess the frequency, outcomes, and impact of high-risk procedures receiving preoperative multidisciplinary review in adult cervical deformity (ACD) patients.

Methods: ACD patients were stratified by whether they underwent high-risk review (HRR). High-risk patients were defined as meeting ≥ 1 of the following criteria: anterior-posterior cervical deformity fusion ≥ 3 levels; planned 3-column osteotomy, vertebral column resection, and/or anterior column refinement; deformity correction with severe baseline neurological deficit; severe baseline myelopathy (modified Japanese Orthopaedic Association score < 11); and severe osteoporosis with fusion ≥ 4 levels. Differences in demographic characteristics, radiographic outcomes, and complication rates were assessed via means comparison. Adjusting for baseline age and modified ACD frailty index, follow-up univariate 1-way ANCOVA was performed to assess postoperative outcomes. Logistic regressions assessed the impact of committee review on prediction of complications or reoperation.

Results: Of 149 ACD patients (mean ± SD age 57.5 ± 10.9 years, 58.2% female, BMI 28.5 ± 7.8 kg/m2), 51.0% (n = 76) underwent committee review. At baseline, cohorts were comparable in terms of age, sex, and BMI, although patients undergoing HRR (HRR+) were frailer according to the modified ACD frailty index (p < 0.001). HRR+ patients were also significantly more likely to have a history of myocardial infarction (p = 0.045). Radiographically, HRR+ patients were more likely to have more severe deformity in terms of T1 slope minus cervical lordosis (p = 0.031) and C2-7 sagittal vertical axis (p < 0.001) compared to patients who did not undergo high-risk review (HRR-). Perioperatively, HRR- patients had significantly greater mean operative time (p < 0.001) and were more likely to undergo any osteotomy (p = 0.020) or 3-column osteotomy (p = 0.045), although total estimated blood loss, length of stay, surgical intensive care unit admissions, and discharge dispositions were comparable between groups (all p > 0.05). Rates of any complications and mortality were also comparable between groups (all p > 0.05). HRR+ patients demonstrated lower reoperation rates (p = 0.037). Yet, adjusted regression revealed that HRR was neither independently predictive of intraoperative major complications nor reoperation (all p > 0.05).

Conclusions: Implementation of high-risk committees is associated with a lower frequency of high-risk procedures over time. However, the risk of complications is not necessarily diminished after the establishment of such committees.

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来源期刊
Journal of neurosurgery. Spine
Journal of neurosurgery. Spine 医学-临床神经学
CiteScore
5.10
自引率
10.70%
发文量
396
审稿时长
6 months
期刊介绍: Primarily publish original works in neurosurgery but also include studies in clinical neurophysiology, organic neurology, ophthalmology, radiology, pathology, and molecular biology.
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