Qiyue Zhang , Tao Yan , Yujing Tong , Ming Zhang , Shaogang Wang , Lili Tan , Qiang Wang , Zengqian Liu , Zhefeng Zhang , Dan Zhang
{"title":"反应熔体渗透的可降解Mg-Fe互渗相复合材料","authors":"Qiyue Zhang , Tao Yan , Yujing Tong , Ming Zhang , Shaogang Wang , Lili Tan , Qiang Wang , Zengqian Liu , Zhefeng Zhang , Dan Zhang","doi":"10.1016/j.msea.2025.148876","DOIUrl":null,"url":null,"abstract":"<div><div>Mg-Fe composites have shown great potential as biodegradable implants for tissue defect regeneration and repair. However, these composites generally exhibit a single continuous structure, which can hinder the degradation process and even lead to inflammatory reactions. In this study, a series of Mg-Fe composites, where the Mg and Fe phases are topologically continuous and interwoven in three-dimensional space, were fabricated. The composition, structure, mechanical properties, <em>in vitro</em> degradation behavior, and biological performance of the composites were characterized and evaluated. The results demonstrate a potential of the Mg-Fe interpenetrating-phase composites as a fully biodegradable biomaterial for bone defect repair.</div></div>","PeriodicalId":385,"journal":{"name":"Materials Science and Engineering: A","volume":"944 ","pages":"Article 148876"},"PeriodicalIF":7.0000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biodegradable Mg-Fe interpenetrating-phase composites by reactive melt infiltration\",\"authors\":\"Qiyue Zhang , Tao Yan , Yujing Tong , Ming Zhang , Shaogang Wang , Lili Tan , Qiang Wang , Zengqian Liu , Zhefeng Zhang , Dan Zhang\",\"doi\":\"10.1016/j.msea.2025.148876\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Mg-Fe composites have shown great potential as biodegradable implants for tissue defect regeneration and repair. However, these composites generally exhibit a single continuous structure, which can hinder the degradation process and even lead to inflammatory reactions. In this study, a series of Mg-Fe composites, where the Mg and Fe phases are topologically continuous and interwoven in three-dimensional space, were fabricated. The composition, structure, mechanical properties, <em>in vitro</em> degradation behavior, and biological performance of the composites were characterized and evaluated. The results demonstrate a potential of the Mg-Fe interpenetrating-phase composites as a fully biodegradable biomaterial for bone defect repair.</div></div>\",\"PeriodicalId\":385,\"journal\":{\"name\":\"Materials Science and Engineering: A\",\"volume\":\"944 \",\"pages\":\"Article 148876\"},\"PeriodicalIF\":7.0000,\"publicationDate\":\"2025-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Materials Science and Engineering: A\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0921509325011001\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Science and Engineering: A","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0921509325011001","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Biodegradable Mg-Fe interpenetrating-phase composites by reactive melt infiltration
Mg-Fe composites have shown great potential as biodegradable implants for tissue defect regeneration and repair. However, these composites generally exhibit a single continuous structure, which can hinder the degradation process and even lead to inflammatory reactions. In this study, a series of Mg-Fe composites, where the Mg and Fe phases are topologically continuous and interwoven in three-dimensional space, were fabricated. The composition, structure, mechanical properties, in vitro degradation behavior, and biological performance of the composites were characterized and evaluated. The results demonstrate a potential of the Mg-Fe interpenetrating-phase composites as a fully biodegradable biomaterial for bone defect repair.
期刊介绍:
Materials Science and Engineering A provides an international medium for the publication of theoretical and experimental studies related to the load-bearing capacity of materials as influenced by their basic properties, processing history, microstructure and operating environment. Appropriate submissions to Materials Science and Engineering A should include scientific and/or engineering factors which affect the microstructure - strength relationships of materials and report the changes to mechanical behavior.