Nighttime sleep duration and dual management of blood pressure and glycemia in Chinese with comorbid hypertension and diabetes.

To characterize the associations between nighttime sleep duration and control of blood pressure (BP) and glycemia in individuals with comorbid hypertension and diabetes, we conducted a cross-sectional analysis of 2794 participants aged ≥ 50 years with confirmed diabetes and hypertension. Participants were categorized into five self-reported nighttime sleep duration groups: < 6 h, 6-7 h, 7-8 h, 8-9 h, and > 9 h. Multivariable logistic regression models were used to evaluate associations between sleep duration and BP/glycemic control, with adjustment for demographic, clinical, and behavioral confounders. We observed that prolonged sleep duration (> 9 h) was independently associated with uncontrolled BP after confounder adjustment. Subgroup analyses revealed that short sleep duration (< 6 h and 6-7 h) was linked to uncontrolled BP among males, whereas prolonged sleep duration was associated with uncontrolled BP among females, participants under 65 years, those with regular medication adherence, and non-nappers. For glycemic control, prolonged sleep duration conferred a protective effect among normal-weight individuals, but this association was not evident in the overall sample. Our results suggested that BP regulation may play a dominant role in competitive metabolic regulation demands compared to glycemic regulation. We recommended that individualized interventions aimed at modifying the habitual sleep duration of patients with comorbidities may be a crucial strategy to enhance BP and blood glucose management.