大脑皮层深层更容易患阿尔茨海默病。

IF 15 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-07-23 DOI:10.1016/j.neuron.2025.06.022

S Zehra H Kazmi, Corette J Wierenga

引用次数: 0

摘要

网络高兴奋性是阿尔茨海默病（AD）早期的标志之一。在这一期的《神经元》杂志上，Papanikolaou1及其同事表明，ad介导的改变始于皮层深层的兴奋抑制亚回路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Deep cortical layers are more vulnerable in Alzheimer's disease.

Network hyperexcitability is one of the hallmarks of the early stage of Alzheimer's disease (AD). In this issue of Neuron, Papanikolaou¹ and coworkers show that AD-mediated alterations start at the excitatory-inhibitory subcircuit in the deep layers of the cortex.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.