基于死亡数据的简单模拟的发病率重建。

IF 1.7 4区 数学 Q3 BIOLOGY
Biometrics Pub Date : 2025-07-03 DOI:10.1093/biomtc/ujaf088
Simon N Wood
{"title":"基于死亡数据的简单模拟的发病率重建。","authors":"Simon N Wood","doi":"10.1093/biomtc/ujaf088","DOIUrl":null,"url":null,"abstract":"<p><p>Daily deaths from an infectious disease provide a means for retrospectively inferring daily incidence, given knowledge of the infection-to-death interval distribution. Existing methods for doing so rely either on fitting simplified non-linear epidemic models to the deaths data or on spline based deconvolution approaches. The former runs the risk of introducing unintended artefacts via the model formulation, while the latter may be viewed as technically obscure, impeding uptake by practitioners. This note proposes a simple simulation based approach to inferring fatal incidence from deaths that requires minimal assumptions, is easy to understand, and allows testing of alternative hypothesized incidence trajectories. The aim is that in any future situation similar to the COVID pandemic, the method can be easily, rapidly, transparently, and uncontroversially deployed as an input to management.</p>","PeriodicalId":8930,"journal":{"name":"Biometrics","volume":"81 3","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Simple simulation based reconstruction of incidence rates from death data.\",\"authors\":\"Simon N Wood\",\"doi\":\"10.1093/biomtc/ujaf088\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Daily deaths from an infectious disease provide a means for retrospectively inferring daily incidence, given knowledge of the infection-to-death interval distribution. Existing methods for doing so rely either on fitting simplified non-linear epidemic models to the deaths data or on spline based deconvolution approaches. The former runs the risk of introducing unintended artefacts via the model formulation, while the latter may be viewed as technically obscure, impeding uptake by practitioners. This note proposes a simple simulation based approach to inferring fatal incidence from deaths that requires minimal assumptions, is easy to understand, and allows testing of alternative hypothesized incidence trajectories. The aim is that in any future situation similar to the COVID pandemic, the method can be easily, rapidly, transparently, and uncontroversially deployed as an input to management.</p>\",\"PeriodicalId\":8930,\"journal\":{\"name\":\"Biometrics\",\"volume\":\"81 3\",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biometrics\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://doi.org/10.1093/biomtc/ujaf088\",\"RegionNum\":4,\"RegionCategory\":\"数学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biometrics","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1093/biomtc/ujaf088","RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

在了解感染至死亡间隔分布的情况下,传染病的每日死亡人数为回顾性推断每日发病率提供了一种手段。现有的方法要么依赖于将简化的非线性流行病模型拟合到死亡数据上,要么依赖于基于样条的反卷积方法。前者有通过模型公式引入意想不到的工件的风险,而后者可能在技术上被认为是模糊的,阻碍了从业者的吸收。本说明提出了一种简单的基于模拟的方法,从死亡中推断致命发病率,这种方法需要最少的假设,易于理解,并允许测试其他假设的发病率轨迹。其目的是,在未来任何类似于COVID大流行的情况下,该方法都可以轻松,快速,透明和无争议地作为管理投入而部署。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simple simulation based reconstruction of incidence rates from death data.

Daily deaths from an infectious disease provide a means for retrospectively inferring daily incidence, given knowledge of the infection-to-death interval distribution. Existing methods for doing so rely either on fitting simplified non-linear epidemic models to the deaths data or on spline based deconvolution approaches. The former runs the risk of introducing unintended artefacts via the model formulation, while the latter may be viewed as technically obscure, impeding uptake by practitioners. This note proposes a simple simulation based approach to inferring fatal incidence from deaths that requires minimal assumptions, is easy to understand, and allows testing of alternative hypothesized incidence trajectories. The aim is that in any future situation similar to the COVID pandemic, the method can be easily, rapidly, transparently, and uncontroversially deployed as an input to management.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Biometrics
Biometrics 生物-生物学
CiteScore
2.70
自引率
5.30%
发文量
178
审稿时长
4-8 weeks
期刊介绍: The International Biometric Society is an international society promoting the development and application of statistical and mathematical theory and methods in the biosciences, including agriculture, biomedical science and public health, ecology, environmental sciences, forestry, and allied disciplines. The Society welcomes as members statisticians, mathematicians, biological scientists, and others devoted to interdisciplinary efforts in advancing the collection and interpretation of information in the biosciences. The Society sponsors the biennial International Biometric Conference, held in sites throughout the world; through its National Groups and Regions, it also Society sponsors regional and local meetings.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信