近视眼视网膜裂临床特征的多模态分析。

IF 2.8 3区 医学 Q1 OPHTHALMOLOGY
Jiaxin Tian, Yinghan Zhang, Kai Cao, Shanshan Huang, Ningli Wang, Yue Qi
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引用次数: 0

摘要

目的:分析近视性视网膜裂(MR)的临床特点、危险因素及严重程度。方法:采用病例对照研究方法,选取高度近视伴MR者200只,不伴MR者398只。所有参与者都记录了人口统计学特征和病史。评估眼轴长度(AXL)、视网膜前膜(ERMs)、玻璃体视网膜牵拉(VT)、穹顶状黄斑(DSM)、黄斑向外巩膜高度(MOSH)和中央凹下CT来描述眼部特征。单因素分析用于分析有MR和没有MR的眼睛之间的特征差异,以及不同MR等级的眼睛之间的特征差异。随后,进行多因素logistic回归,以确定MR及其严重程度相关的重要危险因素。结果:在单因素分析中,与未做MR的眼相比,MR眼有更多的角膜屈光手术,年龄更大,AXL更长,MOSH更大,中央凹下CT更薄,ERMs, VT和垂直DSM的发生率更高(均p)。结论:ERMs, VT,较高的MOSH和中央凹下脉络膜变薄是MR及其严重程度升级的重要危险因素,而轴向延长与MR等级降低相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multimodal analysis of clinical characteristics associated with myopic retinoschisis.

Purpose: To analyse the clinical characteristics and risk factors associated with myopic retinoschisis (MR) and its severity.

Methods: In the case-control study, 200 highly myopic eyes with MR and 398 without MR were enrolled. All participants have recorded demographic characteristics and medical history. Axial length (AXL), epiretinal membranes (ERMs), vitreoretinal traction (VT), dome-shaped macula (DSM), macular outward scleral height (MOSH), and subfoveal CT were evaluated to describe ocular characteristics. Univariate analysis was used to analyse the differences in characteristics between the eyes with and without MR, as well as among the eyes exhibiting varying grades of MR. Following this, multivariate logistic regression was conducted to identify significant risk factors associated with MR and its severity.

Results: In univariate analysis, the MR eyes had more keratorefractive surgeries, older age, longer AXL, greater MOSH, thinner subfoveal CT, higher rates of ERMs, VT as well as vertical DSM than the eyes without MR (all p < 0.05). Besides, there were significant differences in age, AXL, subfoveal CT, MOSH and rate of keratorefractive surgery, ERM as well as VT among different severities of MR (all p < 0.05). The further multivariate analysis revealed ERMs, VT, greater MOSH and subfoveal choroidal thinning were significantly associated with MR and its severity escalation (all p < 0.05), whereas a longer AXL was correlated with a decrease in MR severity (p = 0.018).

Conclusions: ERMs, VT, higher MOSH and subfoveal choroidal thinning were significant risk factors for MR and its severity escalation, while axial elongation correlated with lower grades of MR.

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来源期刊
Acta Ophthalmologica
Acta Ophthalmologica 医学-眼科学
CiteScore
7.60
自引率
5.90%
发文量
433
审稿时长
6 months
期刊介绍: Acta Ophthalmologica is published on behalf of the Acta Ophthalmologica Scandinavica Foundation and is the official scientific publication of the following societies: The Danish Ophthalmological Society, The Finnish Ophthalmological Society, The Icelandic Ophthalmological Society, The Norwegian Ophthalmological Society and The Swedish Ophthalmological Society, and also the European Association for Vision and Eye Research (EVER). Acta Ophthalmologica publishes clinical and experimental original articles, reviews, editorials, educational photo essays (Diagnosis and Therapy in Ophthalmology), case reports and case series, letters to the editor and doctoral theses.
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