非二价精神病理学:通过元控制重新思考精神障碍。

IF 7.9 1区 医学 Q1 BEHAVIORAL SCIENCES
Lorenza Colzato , Hongchi Zhang , Veit Roessner , Christian Beste , Bernhard Hommel
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引用次数: 0

摘要

精神病理学的传统方法基于二价或二元观点(健康vs.疾病),往往模糊了对症状、波动、合并症的异质性以及精神病理学之间的关系/界限的理解。最近的研究领域标准(RDoC)方法识别了这些问题,但没有提供机械的解决方案。我们提出了一种基于神经认知原理的新型非二元方法,该原理来源于完善的、机制透明的精神病理学元控制状态模型(MSMp)。我们建议(1)完全放弃现象学衍生的精神病理学分类;(2)用同一理论解释功能行为和功能失调行为;(3)从基本机制重构行为观察。与RDoC的目标一致,我们的机制描述允许在其核心(负责任的机制)上处理、分析和治疗故障,而不是关注可能不表明常见问题的可观察症状。我们以理论为指导,以证据为基础的方法有可能促进对精神病理学的新的机制理解,提高诊断标准的权重,并使干预更有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-bivalent psychopathology: Rethinking mental disorders through metacontrol
Traditional approaches to psychopathology are based on a bivalent or binary view (healthy vs. ill), oftentimes obscuring an understanding of the heterogeneity of symptoms, fluctuations, comorbidities, and of relationships/boundaries between psychopathologies. The recent Research Domain Criteria (RDoC) approach recognizes these problems without providing mechanistic solutions. We propose a novel non-binary approach based on neurocognitive principles derived from the well-established, mechanistically transparent Metacontrol State Model of psychopathology (MSMp). We suggest (1) abandoning phenomenologically-derived classifications of psychopathologies altogether; (2) explaining functional and dysfunctional behavior by means of the same theory; and (3) reconstructing behavioral observations from basic mechanisms. In line with the ambitions of RDoC, our mechanistic account allows addressing, analyzing, and treating malfunctioning at its very core—the responsible mechanism, rather than focusing on observable symptoms that may not indicate a common problem. Our theory-guided, evidence-based approach has the potential to foster a novel mechanistic understanding of psychopathology, improve diagnostic criteria weighting, and make interventions more effective.
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来源期刊
CiteScore
14.20
自引率
3.70%
发文量
466
审稿时长
6 months
期刊介绍: The official journal of the International Behavioral Neuroscience Society publishes original and significant review articles that explore the intersection between neuroscience and the study of psychological processes and behavior. The journal also welcomes articles that primarily focus on psychological processes and behavior, as long as they have relevance to one or more areas of neuroscience.
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