Katarzyna Gendera, Stanimir Georgiev, Andreas Eicken, Andrea Amici, Alfred Hager, Maria von Stumm, Daniel Dilber, Peter Ewert, Pinar Bambul Heck
{"title":"儿童主动脉弓修复后复发性狭窄的支架植入术:无再手术的中短期结果。","authors":"Katarzyna Gendera, Stanimir Georgiev, Andreas Eicken, Andrea Amici, Alfred Hager, Maria von Stumm, Daniel Dilber, Peter Ewert, Pinar Bambul Heck","doi":"10.1016/j.rec.2025.07.002","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Stent implantation has become the gold standard for the treatment of native coarctation of the aorta (CoA) and recurrent CoA in adolescents and adults. In smaller children, however, stent implantation remains technically challenging due to anatomical constraints and growth considerations. Furthermore, data on the optimal treatment strategy in this age group are still limited. This study retrospectively analyzed clinical outcomes in young children treated with stent implantation for recurrent aortic arch stenosis.</p><p><strong>Methods: </strong>A total of 101 patients (63 male; 62%) with a body weight of less than 15 kg were treated with endovascular stent implantation for re-stenosis of the reconstructed aortic arch (n = 94; 93%) or native CoA (n = 7; 7%). The median age at the time of stent implantation was 4.8 months (IQR, 3.2-9.6 months) with a median body weight of 5.9 kg (IQR, 4.7-8.4 kg). The median follow-up period was 46.4 months (IQR, 11.0-76.6).</p><p><strong>Results: </strong>All procedures were successful, and no serious complications occurred. The peak-to-peak gradient decreased significantly from a median of 32.5 mmHg (IQR, 17.3-46.0 mmHg) to 0.0 mmHg (IQR, 0.0-2.5 mmHg; P < .005). The diameter of the narrow segment increased from a median of 3.0 mm (IQR, 2.0-4.0 mm) to 6.9 mm (IQR, 6.0 8.0 mm; P < .05). During follow-up, none of the patients required reoperation.</p><p><strong>Conclusions: </strong>Stent implantation is a safe and feasible treatment option in patients with restenosis after complex aortic arch reconstruction or native CoA in whom surgical treatment would pose an elevated risk of complications. However, repeated dilatations and, ultimately, intentional stent fracture are required during follow-up.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Stent implantation for recurrent stenosis after aortic arch repair in small children: short- and mid-term results without reoperations.\",\"authors\":\"Katarzyna Gendera, Stanimir Georgiev, Andreas Eicken, Andrea Amici, Alfred Hager, Maria von Stumm, Daniel Dilber, Peter Ewert, Pinar Bambul Heck\",\"doi\":\"10.1016/j.rec.2025.07.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction and objectives: </strong>Stent implantation has become the gold standard for the treatment of native coarctation of the aorta (CoA) and recurrent CoA in adolescents and adults. In smaller children, however, stent implantation remains technically challenging due to anatomical constraints and growth considerations. Furthermore, data on the optimal treatment strategy in this age group are still limited. This study retrospectively analyzed clinical outcomes in young children treated with stent implantation for recurrent aortic arch stenosis.</p><p><strong>Methods: </strong>A total of 101 patients (63 male; 62%) with a body weight of less than 15 kg were treated with endovascular stent implantation for re-stenosis of the reconstructed aortic arch (n = 94; 93%) or native CoA (n = 7; 7%). The median age at the time of stent implantation was 4.8 months (IQR, 3.2-9.6 months) with a median body weight of 5.9 kg (IQR, 4.7-8.4 kg). The median follow-up period was 46.4 months (IQR, 11.0-76.6).</p><p><strong>Results: </strong>All procedures were successful, and no serious complications occurred. The peak-to-peak gradient decreased significantly from a median of 32.5 mmHg (IQR, 17.3-46.0 mmHg) to 0.0 mmHg (IQR, 0.0-2.5 mmHg; P < .005). The diameter of the narrow segment increased from a median of 3.0 mm (IQR, 2.0-4.0 mm) to 6.9 mm (IQR, 6.0 8.0 mm; P < .05). During follow-up, none of the patients required reoperation.</p><p><strong>Conclusions: </strong>Stent implantation is a safe and feasible treatment option in patients with restenosis after complex aortic arch reconstruction or native CoA in whom surgical treatment would pose an elevated risk of complications. However, repeated dilatations and, ultimately, intentional stent fracture are required during follow-up.</p>\",\"PeriodicalId\":38430,\"journal\":{\"name\":\"Revista española de cardiología (English ed.)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":7.2000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista española de cardiología (English ed.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.rec.2025.07.002\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista española de cardiología (English ed.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.rec.2025.07.002","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Stent implantation for recurrent stenosis after aortic arch repair in small children: short- and mid-term results without reoperations.
Introduction and objectives: Stent implantation has become the gold standard for the treatment of native coarctation of the aorta (CoA) and recurrent CoA in adolescents and adults. In smaller children, however, stent implantation remains technically challenging due to anatomical constraints and growth considerations. Furthermore, data on the optimal treatment strategy in this age group are still limited. This study retrospectively analyzed clinical outcomes in young children treated with stent implantation for recurrent aortic arch stenosis.
Methods: A total of 101 patients (63 male; 62%) with a body weight of less than 15 kg were treated with endovascular stent implantation for re-stenosis of the reconstructed aortic arch (n = 94; 93%) or native CoA (n = 7; 7%). The median age at the time of stent implantation was 4.8 months (IQR, 3.2-9.6 months) with a median body weight of 5.9 kg (IQR, 4.7-8.4 kg). The median follow-up period was 46.4 months (IQR, 11.0-76.6).
Results: All procedures were successful, and no serious complications occurred. The peak-to-peak gradient decreased significantly from a median of 32.5 mmHg (IQR, 17.3-46.0 mmHg) to 0.0 mmHg (IQR, 0.0-2.5 mmHg; P < .005). The diameter of the narrow segment increased from a median of 3.0 mm (IQR, 2.0-4.0 mm) to 6.9 mm (IQR, 6.0 8.0 mm; P < .05). During follow-up, none of the patients required reoperation.
Conclusions: Stent implantation is a safe and feasible treatment option in patients with restenosis after complex aortic arch reconstruction or native CoA in whom surgical treatment would pose an elevated risk of complications. However, repeated dilatations and, ultimately, intentional stent fracture are required during follow-up.