dupilumab引发的急性全身性脓疱病。

IF 1.3 Q2 DERMATOLOGY

Dermatology Reports Pub Date : 2025-07-23 DOI:10.4081/dr.2025.10219

Caterina Mariarosaria Giorgio, Gaetano Licata, Giuseppe Argenziano, Vittorio Tancredi, Anna Balato, Eugenia Veronica Di Brizzi

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引用次数: 0

摘要

我们报告了一例罕见但具有临床意义的急性广泛性脓疱病（AGEP）病例，该病例是在难治性特应性皮炎（AD）患者服用杜匹单抗后发生的。虽然dupilumab被广泛认为是一种安全有效的生物制剂，适用于包括青少年、成人和越来越多的儿童在内的各年龄组的中重度AD，但新出现的报告强调需要对罕见的严重皮肤反应保持警惕。[…]。

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Acute generalized exanthematous pustulosis triggered by dupilumab.

Dear Editor, We present a rare but clinically significant case of acute generalized exanthematous pustulosis (AGEP) following the administration of dupilumab in a patient with refractory atopic dermatitis (AD). While dupilumab is widely regarded as a safe and effective biologic agent for moderate-to-severe AD across age groups - including adolescents, adults, and increasingly children - emerging reports underscore the need to remain vigilant for uncommon, severe cutaneous reactions. [...].

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来源期刊

Dermatology Reports DERMATOLOGY-

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

10 weeks