{"title":"减肥巨头之战…还有其他研究","authors":"Tom Nolan","doi":"10.1136/bmj.r1472","DOIUrl":null,"url":null,"abstract":"Tom Nolan reviews this week’s research Cannabinol—aka CBD—is a modern day tonic for almost any ailment, available in all good vape shops and petrol stations. In 2023, the Food Standards Agency cut the recommended safe dose of CBD from 70 mg per day to 10 mg per day. However, as these are only recommendations for what’s classed as a “novel” food, people will often take much higher doses. A randomised control trial assessed the frequency of abnormal liver enzymes with a higher dose of 5 mg/kg/day. Eight out of 151 participants allocated to take CBD had liver enzyme level elevations greater than three times the upper limit of normal by the end of the 28 …","PeriodicalId":22388,"journal":{"name":"The BMJ","volume":"19 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Battle of the weight loss giants . . . and other research\",\"authors\":\"Tom Nolan\",\"doi\":\"10.1136/bmj.r1472\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tom Nolan reviews this week’s research Cannabinol—aka CBD—is a modern day tonic for almost any ailment, available in all good vape shops and petrol stations. In 2023, the Food Standards Agency cut the recommended safe dose of CBD from 70 mg per day to 10 mg per day. However, as these are only recommendations for what’s classed as a “novel” food, people will often take much higher doses. A randomised control trial assessed the frequency of abnormal liver enzymes with a higher dose of 5 mg/kg/day. Eight out of 151 participants allocated to take CBD had liver enzyme level elevations greater than three times the upper limit of normal by the end of the 28 …\",\"PeriodicalId\":22388,\"journal\":{\"name\":\"The BMJ\",\"volume\":\"19 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The BMJ\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/bmj.r1472\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The BMJ","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/bmj.r1472","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Battle of the weight loss giants . . . and other research
Tom Nolan reviews this week’s research Cannabinol—aka CBD—is a modern day tonic for almost any ailment, available in all good vape shops and petrol stations. In 2023, the Food Standards Agency cut the recommended safe dose of CBD from 70 mg per day to 10 mg per day. However, as these are only recommendations for what’s classed as a “novel” food, people will often take much higher doses. A randomised control trial assessed the frequency of abnormal liver enzymes with a higher dose of 5 mg/kg/day. Eight out of 151 participants allocated to take CBD had liver enzyme level elevations greater than three times the upper limit of normal by the end of the 28 …