Charcot骨关节病:如何识别叠加性骨髓炎?]

IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2025-09-01 Epub Date: 2025-07-23 DOI:10.1007/s00117-025-01488-0
Karl-Friedrich Kreitner
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引用次数: 0

摘要

Charcot骨关节病被定义为一种以周围神经病变为特征的骨破坏过程,缺乏保护性本体感觉,其中不适当的负重导致复发性微创伤,引发促炎过程,病理性骨重塑,关节不稳定,随后关节破坏。最常见的原因是糖尿病,随着时间的推移会导致神经病变。磁共振成像是最重要的成像方式,可以对软组织和骨骼变化进行细微的分析。因此,它在疾病早期阶段的检测、随访期间疾病活动性的评估以及叠加感染和骨髓炎的识别方面发挥着关键作用。软组织感染包括蜂窝织炎、痰肿和脓肿。鬼征是鉴别骨髓炎最有用的诊断标准。皮肤溃疡伴周围软组织感染时,应仔细检查窦道和骨骼是否受累。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Charcot's osteoarthropathy : How to identify a superimposed osteomyelitis?]

Charcot's osteoarthropathy is defined as an osteodestructive process characterized by peripheral neuropathy with lack of protective proprioception in which improper weight bearing leads to recurrent microtrauma, triggering of a proinflammatory process, pathological bone remodeling, joint instability, and subsequent joint destruction. The most common cause is diabetes which can lead to neuropathy over time. Magnetic resonance imaging is the most important imaging modality enabling subtle analysis of soft tissue and bony changes. Thus, it plays a key role in detection of early disease stages, assessment of disease activity during follow-up, and identification of superimposed infections and osteomyelitis. Soft tissue infections comprise cellulitis, phlegmons and abscesses. The ghost-sign is the most helpful diagnostic criterion for identification of osteomyelitis. The presence of a skin ulcer with surrounding soft tissue infection should give rise for a careful search for sinus tract and osseous involvement.

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