{"title":"儿童枕脑病变的诊断与治疗。","authors":"Luca Bartolini, Giulia Savoca, Matteo Tassone, Tiziana Metitieri, Renzo Guerrini","doi":"10.1111/dmcn.16434","DOIUrl":null,"url":null,"abstract":"<p><p>Occipital brain lesions in children represent a significant diagnostic challenge because of the wide spectrum of aetiologies and overlapping clinical features. Early recognition and accurate diagnosis are crucial for effective management and to limit long-term neurological deficits, especially in small children whose symptoms may be subtle. This narrative review evaluates common and less common causes of occipital brain lesions in children, including malformative, vascular, genetic and metabolic, infectious, inflammatory, and neoplastic conditions, examining the wide range of associated clinical presentations. Through a review of the literature and description of real-life observations, we highlight the role of a multidisciplinary diagnostic approach that integrates clinical assessment, neuroimaging, neuropsychology, and targeted testing to determine the underlying aetiology. Early recognition of often subtle visual and cognitive disturbances, coupled with targeted work-up, appropriate referral to subspecialty evaluations, and rapid institution of treatment strategies, can improve the long-term outcome considerably.</p>","PeriodicalId":50587,"journal":{"name":"Developmental Medicine and Child Neurology","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnosis and treatment of occipital brain lesions in children.\",\"authors\":\"Luca Bartolini, Giulia Savoca, Matteo Tassone, Tiziana Metitieri, Renzo Guerrini\",\"doi\":\"10.1111/dmcn.16434\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Occipital brain lesions in children represent a significant diagnostic challenge because of the wide spectrum of aetiologies and overlapping clinical features. Early recognition and accurate diagnosis are crucial for effective management and to limit long-term neurological deficits, especially in small children whose symptoms may be subtle. This narrative review evaluates common and less common causes of occipital brain lesions in children, including malformative, vascular, genetic and metabolic, infectious, inflammatory, and neoplastic conditions, examining the wide range of associated clinical presentations. Through a review of the literature and description of real-life observations, we highlight the role of a multidisciplinary diagnostic approach that integrates clinical assessment, neuroimaging, neuropsychology, and targeted testing to determine the underlying aetiology. Early recognition of often subtle visual and cognitive disturbances, coupled with targeted work-up, appropriate referral to subspecialty evaluations, and rapid institution of treatment strategies, can improve the long-term outcome considerably.</p>\",\"PeriodicalId\":50587,\"journal\":{\"name\":\"Developmental Medicine and Child Neurology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-07-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Developmental Medicine and Child Neurology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/dmcn.16434\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Developmental Medicine and Child Neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/dmcn.16434","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Diagnosis and treatment of occipital brain lesions in children.
Occipital brain lesions in children represent a significant diagnostic challenge because of the wide spectrum of aetiologies and overlapping clinical features. Early recognition and accurate diagnosis are crucial for effective management and to limit long-term neurological deficits, especially in small children whose symptoms may be subtle. This narrative review evaluates common and less common causes of occipital brain lesions in children, including malformative, vascular, genetic and metabolic, infectious, inflammatory, and neoplastic conditions, examining the wide range of associated clinical presentations. Through a review of the literature and description of real-life observations, we highlight the role of a multidisciplinary diagnostic approach that integrates clinical assessment, neuroimaging, neuropsychology, and targeted testing to determine the underlying aetiology. Early recognition of often subtle visual and cognitive disturbances, coupled with targeted work-up, appropriate referral to subspecialty evaluations, and rapid institution of treatment strategies, can improve the long-term outcome considerably.
期刊介绍:
Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA).
For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.