人格组织、童年逆境与偏执思维：调节与中介途径。

IF 2.2 3区医学 Q3 PSYCHIATRY

Psychopathology Pub Date : 2025-07-22 DOI:10.1159/000547518

Jürgen Fuchshuber, Maria Gruber, Karin Feichtinger, Miriam Klauser, Karoline Parth, Nestor Kapusta, Stephan Doering, Victor Blüml

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引用次数: 0

摘要

目的：探讨人格组织、童年创伤与偏执思维的关系。假设人格组织调节和调节偏执与童年逆境之间的联系。方法：患者和对照组的混合样本(N = 119；76%为精神病患者；（71%为女性）根据精神病理学(SCID I &；II, BSI-53)，人格组织（STIPO）和童年创伤（CTQ）。采用贝叶斯路径建模方法分析了中介效应。我们通过估计SPSS宏过程中的交互效应来评估人格组织的潜在调节效应。结果：儿童创伤、人格组织与偏执思维呈正相关（均p < 0.001）。中介分析显示，人格组织在儿童创伤与偏执思维的关系中起部分中介作用（间接效应，B = 0.14, 95% CrI）。[07, .23], p < .01])，但仅在未纠正一般精神症状负荷的情况下。相反，调节分析表明，人格组织调节了这种关系（ΔR²= 0.02，F(6112) = 4.93, p < 0.05），如果控制非特异性精神病理，更强的人格功能障碍强化了童年创伤与偏执思维之间的联系。结论：本研究基本支持人格组织在童年创伤与偏执思维之间的联系中起关键作用的假设，它既是中介，又是调节。这表明人格结构的缺陷部分解释和调节了童年逆境与偏执思想的联系。一般精神病理学在这一关系中的复杂作用被讨论。

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Personality Organization, Childhood Adversity, and Paranoid Thinking: Moderating and mediating pathways.

Objectives: The study investigates the relationship between personality organization, childhood trauma and paranoid thinking. It is hypothesized that personality organization mediates as well as moderates the link between paranoia and childhood adversity.

Methods: A mixed sample of patients and control participants (N = 119; 76% psychiatric patients; 71% female) was diagnostically assessed according to psychopathology (SCID I & II, BSI-53), personality organization (STIPO) and childhood trauma (CTQ). Mediation effects were analyzed within a Bayesian path modelling approach. We assessed potential moderation effects of personality organization by estimating interaction effects in the SPSS macro PROCESS.

Results: Significant positive correlations were found between childhood trauma, personality organization, and paranoid thinking (all p < .001). Mediation analysis showed that personality organization partially mediated the relationship between childhood trauma and paranoid thinking (indirect effect, B = .14, 95% CrI [.07, .23], p < .01), however only if not corrected for general psychiatric symptom load. In contrast, moderation analysis indicated that personality organization moderated the relationship (ΔR² = .02, F(6,112) = 4.93, p < .05), if controlled for unspecific psychopathology, with stronger personality dysfunction intensifying the link between childhood trauma and paranoid thinking.

Conclusions: The study generally supports the hypothesis that personality organization plays a critical role in linking childhood trauma to paranoid thinking, acting as both, mediator and moderator. This suggests that deficits in personality structure partly explain and modulate the association of childhood adversity with paranoid ideation. The complex role of general psychopathology in this relationship is discussed.

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来源期刊

Psychopathology 医学-精神病学

CiteScore

5.10

自引率

5.60%

发文量

审稿时长

>12 weeks

期刊介绍： ''Psychopathology'' is a record of research centered on findings, concepts, and diagnostic categories of phenomenological, experimental and clinical psychopathology. Studies published are designed to improve and deepen the knowledge and understanding of the pathogenesis and nature of psychopathological symptoms and psychological dysfunctions. Furthermore, the validity of concepts applied in the neurosciences of mental functions are evaluated in order to closely bring together the mind and the brain. Major topics of the journal are trajectories between biological processes and psychological dysfunction that can help us better understand a subject’s inner experiences and interpersonal behavior. Descriptive psychopathology, experimental psychopathology and neuropsychology, developmental psychopathology, transcultural psychiatry as well as philosophy-based phenomenology contribute to this field.