Brandi M Mize, Emily Laskey, Gregory L Damhorst, Colleen S Kraft, Guillermo A Escobar
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Two Cases of Mycotic Aneurysms Caused by Brucella suis Infection of Aortic Graft Material.
Brucella suis, a zoonotic pathogen, can affect multiple human organ systems causing various clinical manifestations. While aortoiliac involvement is rare worldwide, we report 2 cases of aortic brucellosis following abdominal aortic aneurysm repairs within a 9-year period at a single US institution in Georgia. One case was an infected aortic endograft, which may be the first reported. B suis aortoiliac infections are rare even in endemic areas, thus highlighting how uncommon these cases are in Georgia. Acknowledging the dismal prognosis with symptomatic aortic graft infections, we wish to share our experience in successfully treating them, including an infected aortic endograft. We recommend obtaining a robust history when evaluating individuals with suspected mycotic aneurysms who frequently handle animals. Education on protective equipment and proper handling of animals is imperative to reduce the risk of aortic graft brucellosis infections. Our institutional experience suggests that graft explantation and doxycycline-rifampin are acceptable treatment options.
期刊介绍:
Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.