牙科配方能否预测下颌推进装置治疗阻塞性睡眠呼吸暂停的治疗结果？一项回顾性横断面研究。

IF 4 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of oral rehabilitation Pub Date : 2025-07-22 DOI:10.1111/joor.70006

Constance Cuny, Philippe Kemoun, Florent Destruhaut, Coraline Sipra, Mathieu Marty, Delphine Comtesse-Maret, Frédéric Vaysse

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引用次数: 0

摘要

研究目的：阻塞性睡眠呼吸暂停（OSA）是一种普遍存在的睡眠障碍，具有重要的健康影响。虽然全牙化与OSA风险增加有关，但与部分全牙化的关系尚不清楚。本研究旨在探讨口腔配方在OSA严重程度和下颌推进装置（MAD）治疗结果中的作用。方法：一项回顾性研究最初纳入560例通过多导睡眠图（PSG）诊断为OSA的患者。根据预定义的纳入标准，选择75名患者进行分析。使用基线骨断层摄影评估牙齿参数。客观治疗结果在治疗3个月后通过基线PSG和重复PSG与MAD进行评估。分析OSA严重程度和MAD治疗结果的差异，并分析各组间牙参数的相关性。结果：MAD治疗后患者的基线中位呼吸暂停-低通气指数（AHI）由27.82±16.77降至15.51±13.33。部分义齿参数与基线OSA严重程度无显著差异或相关。然而，缺失的牙齿数量与重新评估的AHI （rAHI）之间存在相关性，并且咀嚼系数与rAHI之间也存在负相关。下颌全牙（主要是单侧或双侧后牙）与MAD治疗结果呈正相关。结论：本研究证实了OSA患者的全牙化参数与MAD治疗结果之间的相关性。牙医和睡眠医学专家之间的合作对于全面的OSA管理至关重要，包括口腔健康评估。试验注册：经过数据保护官的评估和验证，并根据通用数据保护条例，本研究符合所有标准，并在图卢兹大学医院数据研究登记册中注册（注册号：RnIPH 2023-81），并由MR-004 （CNIL编号：2206723 v 0）覆盖。本研究获得图卢兹大学医院批准，并确认完全符合上述报告的伦理要求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Does the Dental Formula Predict Therapy Outcomes of Obstructive Sleep Apnoea Treated With a Mandibular Advancement Device ? A Retrospective Cross-Sectional Study

查看原文本刊更多论文

Does the Dental Formula Predict Therapy Outcomes of Obstructive Sleep Apnoea Treated With a Mandibular Advancement Device ? A Retrospective Cross-Sectional Study

Study Objectives

Obstructive sleep apnoea (OSA) is a prevalent sleep disorder with significant health implications. While complete edentulism has been associated with an increased OSA risk, the relationship with partial edentulism remains unclear. This study aimed to investigate the role of dental formula in OSA severity and mandibular advancement device (MAD) therapy outcomes.

Methods

A retrospective study initially included 560 patients diagnosed with OSA by polysomnography (PSG). A subset of 75 patients was selected for analysis based on predefined inclusion criteria. Dental parameters were assessed using baseline orthopantomograms. Objective treatment outcomes were evaluated using baseline PSG and repeat PSG with MAD after 3 months of therapy. Differences in OSA severity and MAD treatment outcomes were analysed, and dental parameters were correlated between groups.

Results

The median baseline apnoea–hypopnoea index (AHI) significantly reduced from 27.82 ± 16.77 to 15.51 ± 13.33 following MAD therapy. Partial edentulism parameters did not differ significantly or correlate with baseline OSA severity. However, a correlation was observed between the number of missing teeth and reassessed AHI (rAHI), and an inverse correlation between the masticatory coefficient and rAHI was also noted. Mandibular edentulism—primarily unilateral or bilateral posterior—was positively correlated with MAD treatment outcomes.

Conclusion

This study demonstrates a correlation between edentulism parameters and MAD treatment outcomes in patients with OSA. Collaboration between dentists and sleep medicine specialists is crucial for comprehensive OSA management, including oral health assessment.

Trial Registration: After evaluation and validation by the data protection officer and according to the General Data Protection Regulation, this study met all the criteria and was registered in the register of data study of the Toulouse University Hospital (Register Number: RnIPH 2023–81) and covered by the MR-004 (CNIL Number: 2206723 v 0).

This study was approved by Toulouse University Hospital and confirmed that ethical requirements were fully met in the above report.

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来源期刊

Journal of oral rehabilitation 医学-牙科与口腔外科

CiteScore

5.60

自引率

10.30%

发文量

116

审稿时长

4-8 weeks

期刊介绍： Journal of Oral Rehabilitation aims to be the most prestigious journal of dental research within all aspects of oral rehabilitation and applied oral physiology. It covers all diagnostic and clinical management aspects necessary to re-establish a subjective and objective harmonious oral function. Oral rehabilitation may become necessary as a result of developmental or acquired disturbances in the orofacial region, orofacial traumas, or a variety of dental and oral diseases (primarily dental caries and periodontal diseases) and orofacial pain conditions. As such, oral rehabilitation in the twenty-first century is a matter of skilful diagnosis and minimal, appropriate intervention, the nature of which is intimately linked to a profound knowledge of oral physiology, oral biology, and dental and oral pathology. The scientific content of the journal therefore strives to reflect the best of evidence-based clinical dentistry. Modern clinical management should be based on solid scientific evidence gathered about diagnostic procedures and the properties and efficacy of the chosen intervention (e.g. material science, biological, toxicological, pharmacological or psychological aspects). The content of the journal also reflects documentation of the possible side-effects of rehabilitation, and includes prognostic perspectives of the treatment modalities chosen.